Courses
Terms offered: Spring 2024, Spring 2023, Spring 2022
Students in this course will critically examine modern methods of biological investigations and their social implications. Relevant literature will be used to present basic biological concepts that address the cultural, technological and health aspects of current topics in the biological sciences. Designing and evaluating scientific questions will be stressed.
Current Topics in the Biological Sciences: Read More [+]
Rules & Requirements
Prerequisites: Suitable for freshmen who plan to major in a biological science
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructor: Matsui
Terms offered: Fall 2024, Spring 2024, Fall 2023
The Berkeley Seminar Program has been designed to provide new students with the opportunity to explore an intellectual topic with a faculty member in a small-seminar setting. Berkeley Seminars are offered in all campus departments, and topics vary from department to department and semester to semester. Final assessment to be decided by the instructor when the class is offered.
Freshman Seminars: Read More [+]
Rules & Requirements
Prerequisites: Open to freshmen only
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: The grading option will be decided by the instructor when the class is offered. Alternative to final exam.
Formerly known as: Molecular and Cell Biology 90A
Terms offered: Spring 2014, Spring 2012
An introduction for students who do not intend to major in biology but who wish to satisfy their breadth requirement in Biological Sciences. Some major concepts of modern biology, ranging from the role of DNA and the way cells communicate, to interactions of cells and creatures with their environment, will be discussed without jargon and with attention to their relevance in contemporary life and culture.
Big Ideas in Cell Biology: Read More [+]
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Wilt
Also listed as: L & S C30X
Terms offered: Fall 2024, Summer 2024 8 Week Session, Fall 2023
A comprehensive introduction to human biology. The course will concentrate on basic mechanisms underlying human life processes, including cells and membranes; nerve and muscle function; cardiovascular, respiratory, renal, and gastrointestinal physiology; metabolism, endocrinology, and reproduction.
Introduction to Human Physiology: Read More [+]
Rules & Requirements
Prerequisites: One year high school or college chemistry
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer: 8 weeks - 6 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Ball
Terms offered: Fall 2024, Summer 2024 Second 6 Week Session, Fall 2023
Experiments and demonstrations are designed to amplify and reinforce information presented in 32. Exercises include investigations into the structure and function of muscle, nerve, cardiovascular, renal, respiratory, endocrine, and blood systems.
Introduction to Human Physiology Laboratory: Read More [+]
Rules & Requirements
Prerequisites: 32 or may be taken concurrently
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture and 3 hours of laboratory per week
Summer:
6 weeks - 2 hours of lecture and 8 hours of laboratory per week
8 weeks - 2 hours of lecture and 6 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructor: Ball
Terms offered: Spring 2024, Spring 2023, Spring 2022
Innovations in bioengineering and use of stem cells will significantly impact our ability to combat human disease, genetic disorders and physiological dysfunction. An understanding of human stem cell biology will be critical to make informed decisions on our health and public policy.
Stem Cell Biology, Ethics and Societal Impact: Read More [+]
Rules & Requirements
Repeat rules: Course may be repeated for credit with instructor consent.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Firestone, Ball
Stem Cell Biology, Ethics and Societal Impact: Read Less [-]
Terms offered: Spring 2016, Spring 2013, Summer 2012 8 Week Session
Basic communication of inheritance; gene mapping; gene expression and genetic disease in animals and humans; social inheritance of genetics.
Genetics and Society: Read More [+]
Rules & Requirements
Prerequisites: Primarily for students not specializing in biology
Credit Restrictions: Students will receive no credit for Molecular and Cell Biology 41 after completing Biology 1A, Biology 1B, or Letters and Science 18.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 1 hour of discussion per week
Summer:
6 weeks - 7.5 hours of lecture per week
8 weeks - 6 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Terms offered: Spring 2017, Spring 2015, Spring 2014
This is a Discovery Course for non-Biology majors designed to introduce lower-division college students to biology through the lens of the contemporary problems facing people, the planet and the species of the planet. Modern genetic contributions will be presented on such issues as genetic engineering of plants and animals, the emergence of new pathogens, the role of genetic variation among individuals, and the extent to which DNA is and isn’t destiny. Each week will close with the presentation and discussion of a defining biological challenge facing the world.
Biology for Voters: Read More [+]
Objectives & Outcomes
Student Learning Outcomes: The learning objectives will be, at one end, to understand what an experiment is, how is it controlled and what does one need to know about an experiment to be able to rely upon any conclusion. That is the fundamental issue in all science, and is frequently overlooked in many media accounts of science. A second objective is to learn enough of the language of biology to be able to ask the kind of informed questions that we would want all elected representatives to pay attention to. A third objective is for students to cultivate confidence that through non-specialized information sources they can become informed consumers of contemporary scientific thought, and to develop those habits of intellect to think about evidence in a scientific manner. A fourth objective is for students to enjoy the abundance of high quality books, articles and multimedia that will enable a lifetime of discovery outside the structure of a college course.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Rine, Urnov
Also listed as: L & S C30Y
Terms offered: Spring 2024, Spring 2023, Spring 2022
Course will discuss how the immune system resolves, prevents, or causes disease. A general overview of the immune system will be covered in the first five weeks followed by five weeks discussing infectious diseases including anthrax, mad cow, herpes, malaria, tuberculosis, and HIV. In addition, other lectures will focus on current immunology topics including vaccines, autoimmunity, allergy, transplantation, and cancer.
The Immune System and Disease: Read More [+]
Rules & Requirements
Prerequisites: High school chemistry or Chemistry 1A and high school biology or Biology 1A. Biology 1AL is not required
Credit Restrictions: Students will receive no credit for Molecular and Cell Biology 50 after completing Molecular and Cell Biology 102, C100A/Chemistry C130, or Chemistry 135.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Beatty
Terms offered: Fall 2024, Summer 2024 Second 6 Week Session, Fall 2023
Discussion of how infectious agents cause disease and impact society at large. We will examine historical and current examples of plagues and pandemics and consider the question of what we should do to ameliorate the impact of infectious disease in the future. The course is intended for non-majors and will begin by briefly providing necessary background in microbiology and immunology. The primary focus in each subsequent week, however, will be on discussing a particular infectious disease. The course will be broad in scope covering biological, historical, ethical and social implications of each disease.
Plagues and Pandemics: Read More [+]
Rules & Requirements
Credit Restrictions: Students will receive no credit for MCELLBI 55 after completing CHEM C130, MCELLBI 150, MCELLBI C103, MCELLBI 102, or CHEM 135.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Summer: 6 weeks - 7.5 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Beatty, Vance
Terms offered: Summer 2024 First 6 Week Session, Summer 2023 First 6 Week Session, Summer 2022 First 6 Week Session
This course deals with the structure and function of the human nervous system, with an emphasis on how brain physiology and chemistry are related to human behavior. This is a comprehensive introduction to the exciting field of contemporary neuroscience for students of all backgrounds and interests, including those from the humanities and social sciences, as well as physical and biological sciences. The Final Examination will be administered in a proctored setting. See Schedule of Classes for meeting information. This course is web-based.
Brain, Mind, and Behavior: Read More [+]
Rules & Requirements
Credit Restrictions: Students will receive no credit for MCELLBI/PSYCH W61 after taking MCELLBI 61, N61, C61, MCELLBI 104, C100A/Chemistry C130, MCELLBI 110, 130A, 136, 160, C160/Neuroscience C160 or Integrative Biology 132. A deficient grade in MCELLBI 61, N61, OR C61 can be removed with W61. Students cannot credit for both MCELLBI/PSYCH C61 AND Psych 110.
Hours & Format
Summer: 6 weeks - 7 hours of web-based lecture and 2.5 hours of web-based discussion per week
Online: This is an online course.
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Presti
Terms offered: Summer 2019 Second 6 Week Session
This lab course is an introduction to mammalian neuroanatomy for non-MCB majors. We will do dissections, explore physical anatomical models, and observe microscopic structures within preserved brain slices from a variety of mammalian species. The hands-on exploration of anatomy is key to understanding how the different functional regions of the nervous system are interconnected. Besides gaining a better understanding of anatomy, you will gain important scientific skills such as conducting parts of a neurological exam, fluorescent and light microscopy, reading MRI scans and conducting fine dissections. The course will culminate with a group project using the online Allen Brain Atlas to investigate a novel scientific question.
Introduction to Neuroanatomy Lab: Read More [+]
Rules & Requirements
Prerequisites: MCELLBI 63 (may be taken concurrently) or equivalent
Credit Restrictions: Students will receive no credit for Molecular and Cell Biology 63L after taking Molecular and Cell Biology 160L or 163L
Hours & Format
Summer: 6 weeks - 8 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Alternative to final exam.
Instructor: Ball
Terms offered: Spring 2019
This course offers an introduction to the field of biotechnology and will cover the history of the field, its impact on medicine and society, key methodologies, important therapeutic areas, and the range of career options available in the biopharmaceutical industry. In addition to lectures on innovation and entrepreneurship, students will hear from lecturers with expertise ranging from molecular biology to clinical trial design and interpretation. Several case studies of historically impactful scientists, entrepreneurs, and biotherapeutic companies will be presented. Students will work in teams to create and develop novel biotechnology company ideas to present in class. Intended for students interested in the Biology+Business program.
Introduction to the Biotechnology Field and Industry: Read More [+]
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Alternative to final exam.
Instructors: Kirn, Lasky
Formerly known as: Molecular and Cell Biology C95B/Undergrad. Business Administration C95B
Also listed as: UGBA C95B
Introduction to the Biotechnology Field and Industry: Read Less [-]
Terms offered: Fall 2013, Spring 2013, Fall 2012
Sophomore seminars are small interactive courses offered by faculty members in departments all across the campus. Sophomore seminars offer opportunity for close, regular intellectual contact between faculty members and students in the crucial second year. The topics vary from department to department and semester to semester. Enrollment limited to 15 sophomores.
Sophomore Seminar: Read More [+]
Rules & Requirements
Prerequisites: At discretion of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 1-2 hours of seminar per week
Summer:
6 weeks - 4-6 hours of seminar per week
8 weeks - 3-4 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: The grading option will be decided by the instructor when the class is offered. Final exam required.
Terms offered: Spring 2018, Spring 2017
We will work with a variety of datasets that describe a molecular view of cells and how they divide. We will learn about the processes that cause cells to become specialized (differentiate) and to give rise to cancer (transform). We will analyze data on genetic mutations in cancer that distinguish tumor cells from normal cells. We will learn how mutations are detected by the immune system and the basis of cancer immunotherapy. Finally we will analyze data on clinical trials of cancer immunotherapy to define the correlates of success in curing the disease. The students are expected to gain an understanding of data that reveals the basics of cell physiology and cancer, how immunotherapies of cancer work and their current limitations.
Immunotherapy of Cancer: Success and Failures: Read More [+]
Rules & Requirements
Prerequisites: Foundations of Data Science: COMPSCI C8, DATASCI C8, INFO C8 or STAT C8
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture and 1 hour of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Alternative to final exam.
Instructor: Shastri
Immunotherapy of Cancer: Success and Failures: Read Less [-]
Terms offered: Fall 2024, Fall 2023, Fall 2022
Students will be introduced to the "culture" of the biological sciences, along with an in-depth orientation to the academic life and the culture of the university as they relate to majoring in biology. Students will learn concepts, skills, and information that they can use in their major courses, and as future science professionals.
Studying the Biological Sciences: Read More [+]
Rules & Requirements
Prerequisites: Consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam required.
Instructor: Matsui
Also listed as: INTEGBI C96/PLANTBI C96
Terms offered: Fall 2023, Spring 2023, Fall 2022
Lectures and small group discussions focusing on topics of interest, varying from semester to semester.
Directed Group Study: Read More [+]
Rules & Requirements
Prerequisites: Freshmen and sophomores only
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of directed group study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
Terms offered: Spring 2012, Fall 2009, Spring 2009
Supervised Independent Study: Read More [+]
Rules & Requirements
Prerequisites: 3.3 GPA and consent of instructor
Credit Restrictions: One unit of credit is given for every three hours of work in the lab per week to a maximum of 4 units.
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of independent study per week
Summer:
8 weeks - 1.5-7.5 hours of independent study per week
10 weeks - 1.5-6 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
Terms offered: Spring 2024, Spring 2023, Spring 2022
This course surveys cellular metabolism with a focus on the underlying bioenergetics, mechanisms, and chemistry. Lectures will cover major principles in the biochemistry of metabolism and also highlight selected topics including signaling, transport, metabolic engineering, and human diseases related to metabolic dysfunction. The course is designed for majors in the biochemistry and molecular biology, genetics and development, or immunology emphases.
Biochemistry: Pathways, Mechanisms, and Regulation: Read More [+]
Rules & Requirements
Prerequisites: C100A/Chemistry C130
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Savage, Zoncu, Marletta
Biochemistry: Pathways, Mechanisms, and Regulation: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Thermodynamic and kinetic concepts applied to understanding the chemistry and structure of biomolecules (proteins, DNA, and RNA). Molecular distributions, reaction kinetics, enzyme kinetics. Bioenergetics, energy transduction, and motor proteins. Electrochemical potential, membranes, and ion channels.
Biophysical Chemistry: Physical Principles and the Molecules of Life: Read More [+]
Rules & Requirements
Prerequisites: Chemistry 3A or 112A, Mathematics 1A, Biology 1A and 1AL; Chemistry 3B or 112B recommended
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer: 8 weeks - 5.5 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Also listed as: CHEM C130
Biophysical Chemistry: Physical Principles and the Molecules of Life: Read Less [-]
Terms offered: Fall 2024, Summer 2024 8 Week Session, Spring 2024
A comprehensive survey of the fundamentals of biological chemistry, including the properties of intermediary metabolites, the structure and function of biological macromolecules, the logic of metabolic pathways (both degradative and biosynthetic) and the molecular basis of genetics and gene expression.
Survey of the Principles of Biochemistry and Molecular Biology: Read More [+]
Rules & Requirements
Prerequisites: BIOLOGY 1A and CHEM 3B with minimum grades of C- (or equivalent courses). Recommended: a course in physical chemistry
Credit Restrictions: Students will receive no credit for 102 after taking 100B or C100A/Chemistry C130 or Chemistry 135.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer:
8 weeks - 6 hours of lecture and 2 hours of discussion per week
10 weeks - 4 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Survey of the Principles of Biochemistry and Molecular Biology: Read Less [-]
Terms offered: Spring 2024, Spring 2023, Spring 2022
This course for upper division and graduate students will explore the molecular and cellular basis of microbial pathogenesis. The course will focus on model microbial systems which illustrate mechanisms of pathogenesis. Most of the emphasis will be on bacterial pathogens of mammals, but there will be some discussion of viral and protozoan pathogens. There will be an emphasis on experimental approaches. The course will also include some aspects of bacterial genetics and physiology, immune response to infection, and the cell biology of host-parasite interactions.
Bacterial Pathogenesis: Read More [+]
Rules & Requirements
Prerequisites: BIOLOGY 1A and CHEM 3B
Credit Restrictions: Students will receive no credit for MCELLBI C103 after completing PB HLTH 262.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Portnoy
Also listed as: PLANTBI C103
Terms offered: Fall 2024, Summer 2024 8 Week Session, Spring 2024
This course will introduce students to key concepts in genetic analysis, eukaryotic cell biology, and state-of-the-art approaches in genomic medicine. Lectures will highlight basic knowledge of cellular processes with the basis for human diseases, particularly cancer. Prerequisite courses will have introduced students to the concepts of cells, the central dogma of molecular biology, and gene regulation. Emphasis in this course will be on eukaryotic cell processes, including cellular organization, dynamics, and signaling.
Genetics, Genomics, and Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: BIOLOGY 1A
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer: 8 weeks - 6 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Terms offered: Fall 2024, Spring 2024, Fall 2023
Molecular biology of prokaryotic and eukaryotic cells and their viruses. Mechanisms of DNA replication, transcription, translation. Structure of genes and chromosomes. Regulation of gene expression. Biochemical processes and principles in membrane structure and function, intracellular trafficking and subcellular compartmentation, cytoskeletal architecture, nucleocytoplasmic transport, signal transduction mechanisms, and cell cycle control.
Molecular Biology: Macromolecular Synthesis and Cellular Function: Read More [+]
Rules & Requirements
Prerequisites: C100A (may not be taken concurrently); Plan 1 Emphasis 1 (BMB) majors should take 100B prior to 110
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Molecular Biology: Macromolecular Synthesis and Cellular Function: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Experimental techniques of biochemistry and molecular biology, designed to accompany the lectures in Molecular and Cell Biology 100B and 110.
General Biochemistry and Molecular Biology Laboratory: Read More [+]
Rules & Requirements
Prerequisites: 110 (may be taken concurrently)
Hours & Format
Fall and/or spring: 15 weeks - 2-2 hours of lecture and 6-8 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Also listed as: CHEM C110L
General Biochemistry and Molecular Biology Laboratory: Read Less [-]
Terms offered: Fall 2024, Summer 2024 10 Week Session, Fall 2023
This course will explore the molecular bases for physiological and biochemical diversity among members of the two major domains, Bacteria and Archaea. The ecological significance and evolutionary origins of this diversity will be discussed. Molecular, genetic, and structure-function analyses of microbial cell cycles, adaptive responses, metabolic capability, and macromolecular syntheses will be emphasized.
General Microbiology: Read More [+]
Rules & Requirements
Prerequisites: Biology 1A and 1B
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer: 10 weeks - 5 hours of lecture and 1.5 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Ryan
Also listed as: PLANTBI C112
Terms offered: Fall 2024, Spring 2024, Fall 2023
Experimental techniques of microbiology designed to accompany the lecture in C112 and C148. The primary emphasis in the laboratory will be on the cultivation and physiological and genetic characterization of bacteria. Laboratory exercises will include the observation, enrichment, and isolation of bacteria from selected environments.
General Microbiology Laboratory: Read More [+]
Rules & Requirements
Prerequisites: C112 (may be taken concurrently)
Hours & Format
Fall and/or spring: 15 weeks - 4 hours of laboratory and 1 hour of discussion per week
Summer: 10 weeks - 6 hours of laboratory and 1.5 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructors: Komeili, Traxler
Also listed as: PLANTBI C112L
Terms offered: Spring 2024, Spring 2023, Spring 2022
This course will provide a comparative overview of virus life cycles and strategies viruses use to infect and replicate in hosts. We will discuss virus structure and classification and the molecular basis of viral reproduction, evolution, assembly, and virus-host interactions. Common features used during virus replication and host cellular responses to infection will be covered. Topics also included are common and emerging virus diseases, their control, and factors affecting their spread.
Introduction to Comparative Virology: Read More [+]
Rules & Requirements
Prerequisites: Introductory chemistry (Chemistry 1A or 3A-3B or equivalent) and introductory biology (Biology 1A, 1AL, and 1B or equivalent) and general biochemistry (Molecular and Cell Biology C100A or equivalent--preferably completed but may be taken concurrently)
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1.5 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Glaunsinger
Also listed as: ESPM C138/PLANTBI C114
Terms offered: Fall 2024, Fall 2022, Fall 2021
This course for upper-division and graduate students will broadly survey myriad types of microbial organisms, both procaryote and eucaryote, using a phylogenetic framework to organize the concept of "biodiversity." Emphasis will be on the evolutionary development of the many biochemical themes, how they mold our biosphere, and the organisms that affect the global biochemistry. Molecular mechanisms that occur in different lineages will be compared and contrasted to illustrate fundamental biological strategies. Graduate students additionally should enroll in C216, Microbial Diversity Workshop.
Microbial Diversity: Read More [+]
Rules & Requirements
Prerequisites: Upper-division standing. C112 or consent of instructor and organic chemistry (may be taken concurrently)
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Coates
Formerly known as: 116
Also listed as: PLANTBI C116
Terms offered: Spring 2024, Spring 2023
Students will build on the central metabolic pathways to learn about plant-specific metabolism from a more mechanistic perspective, including photosynthesis, regulation of sugar and starch metabolism, chloroplast-based pathways of inorganic nutrient (nitrogen, sulfur) processing, N2 fixing in free-living and symbiotic bacteria, polyunsaturated fatty acid and oil biosynthesis and accumulation, secondary metabolism, cell-wall structure and biosynthesis. Instruction will focus on a research-based approach, including retrieving and researching the primary literature, and understanding experimental design in modern plant biochemistry.
Advanced Plant Biochemistry: Read More [+]
Rules & Requirements
Prerequisites: A minimum grade of C- in MCELLBI C100A/CHEM C130, MCELLBI 102, MCELLBI 104, MCELLBI 140, PLANTBI 135, or equivalent
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture, 1 hour of discussion, and 1 hour of tutorial per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Merchant
Also listed as: PLANTBI C136
Terms offered: Fall 2024, Fall 2023
This class is designed to introduce students to crucial concepts that underlie the discovery and development of therapeutic modalities. It will cover questions of target discovery and validation; basic properties of therapeutic modalities, such as small molecules, designer proteins, or genome engineering approaches; the design and execution of chemical screens; the medicinal chemistry, pharmacodynamics and -kinetics that is required for drug development; and the steps needed to introduce a new modality into the clinic. Lectures are based on a combination of textbook readings and primary literature and summarized through case studies that highlight critical aspects of drug discovery and development.
Therapeutics Discovery and Development: Read More [+]
Rules & Requirements
Prerequisites: MCELLBI 104 (can be taken concurrently) and MCELLBI C100A/CHEM C130 or MCELLBI 102
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Urnov
Terms offered: Not yet offered
This lab course will familiarize students with general principles of drug discovery and action. The first module focuses on aspects of small molecule function by comparing stoichiometric inhibitors and PROTAC molecules against the BTK kinase. Students will learn how to purify protein, monitor drug binding and in vitro efficiency, and determine effects on cell survival. The second module focuses on genomic therapies by introducing students to principles of CRISPR genome editing. Students will design genome editing strategies and cognate guide RNAs and then perform an editing experiment that replaces a catalytic Cys residue in BTK with Ser. Students will compare stoichiometric inhibitors against BTK to PROTAC in wildtype or mutant cells.
Therapeutics Discovery Laboratory: Read More [+]
Rules & Requirements
Prerequisites: MCELLBI C100A or MCELLBI 102
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture and 8 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Terms offered: Spring 2024
This course will investigate a wide range of topics in cell biology, focusing on modern and classic experimental approaches that have provided important insights, and the relevance of their findings to understanding human health and disease. We will emphasize the importance of quantitative understanding in research topics that are current areas of discovery. We aim to convey an understanding of how cellular structure and function arise as a result of the properties of macromolecules and how understanding the behavior of molecules is needed to explain how cells and organisms operate. This understanding thus also explains what happens when normal cellular functions are impacted, leading to cellular dysfunction and disease.
Cell Biology: from Discovery to Disease: Read More [+]
Rules & Requirements
Prerequisites: Upper Division Standing; MCELLBI 102 or MCELLBI C100A
Credit Restrictions: Students will receive no credit for MCELLBI 130 after completing MCELLBI 130.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Formerly known as: Molecular and Cell Biology 130
Also listed as: NUSCTX C130
Terms offered: Fall 2024, Fall 2023, Fall 2022
The course is designed for students interested in learning about the molecular and cell biology of cancer and how this knowledge is being applied to the prevention, diagnosis and therapy of cancer. Topics covered include tumor pathology and epidemiology; tumor viruses and oncogenes; intracellular signaling; tumor suppressors; multi-step carcinogenesis and tumor progression; genetic instability in cancer; tumor-host interactions; invasion and metastasis; tumor immunology; cancer therapy.
Biology of Human Cancer: Read More [+]
Rules & Requirements
Prerequisites: Biology 1A, 1AL, 1B and MCELLBI 102; MCELLBI 110 or 104 (may be taken concurrently)
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Formerly known as: 135G
Terms offered: Fall 2024, Spring 2024, Fall 2023
Experimental analyses of central problems in cell biology and physiology using modern techniques, including DNA cloning and protein biochemistry, fluorescence microscopy of the cytoskeleton and organelles, DNA transfection and cell cycle analysis of cultured mammalian cells, RNA interference and drug treatments to analyze ion channel function in cell contractility and intracellular signaling, and somatosensation.
Physiology and Cell Biology Laboratory: Read More [+]
Rules & Requirements
Prerequisites: BIOLOGY 1A
Credit Restrictions: Students will receive no credit for 133L after taking 130L.
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture and 7 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Terms offered: Spring 2024, Fall 2022, Spring 2022
This course focuses on the structure, functions, and dynamics of eukaryotic chromosomes and their organization within cell nuclei. All life on earth relies on genetic information, which is encoded within nucleic acids (DNA and RNA). Most organisms have DNA-based genomes; bacterial and archaeal genomes typically comprise a single circular DNA molecule, while the genomes of most eukaryotes are divided into a variable number of linear DNA molecules. These contiguous DNA strands, along with the associated proteins and other components that contribute to their organization and function, are known as “chromosomes.”
Genome Organization and Nuclear Dynamics: Read More [+]
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Dernburg, Karpen
Also listed as: PLANTBI C134
Terms offered: Fall 2024, Fall 2023, Fall 2022
Molecular mechanisms by which hormones elicit specific responses and regulate gene expression; hormone-receptor interaction; synthesis, transport and targeting of hormones, growth factors and receptors.
Topics in Cell and Developmental Biology: Molecular Endocrinology: Read More [+]
Rules & Requirements
Prerequisites: BIOLOGY 1A. Recommended: MCELLBI 102 or MCELLBI C110A/CHEM C130 (may be taken concurrently)
Credit Restrictions: Students will receive no credit for Molecular and Cell Biology 135A after taking Physiology 142.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Firestone
Topics in Cell and Developmental Biology: Molecular Endocrinology: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Principles of mammalian (primarily human) physiology emphasizing physical, chemical, molecular and cellular bases of functional biology. The following topics will be covered: cellular and membrane ion and nonelectrolyte transport; cell and endocrine regulation; autonomic nervous system regulation; skeletal, smooth and cardiac muscle; cardiovascular physiology; respiration; renal physiology; gastrointestinal physiology. Discussion section led by Graduate Student Instructor will review material covered in lecture.
Physiology: Read More [+]
Rules & Requirements
Prerequisites: Biology 1A, 1AL, 1B, Physics 8A. Physics 8B recommended
Credit Restrictions: Students will receive no credit for Molecular and Cell Biology 136 after completing Integrative Biology 132.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer:
6 weeks - 8 hours of lecture and 3 hours of discussion per week
8 weeks - 6 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Terms offered: Spring 2024, Spring 2022, Spring 2020
Biology is being revolutionized by new experimental techniques that have made it possible to measure the inner workings of molecules, cells and multicellular organisms with unprecedented precision. The objective of this course is to explore this deluge of quantitative data through the use of biological numeracy. We will develop theoretical models that make precise predictions about biological phenomena. These predictions will be tested through the hands-on analysis of experimental data and by performing numerical simulations using Matlab. A laptop is required for this course, but no previous programming experience is required.
Physical Biology of the Cell: Read More [+]
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of laboratory per week
Summer: 8 weeks - 6 hours of lecture and 2 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Alternative to final exam.
Instructor: Garcia
Terms offered: Fall 2024, Spring 2024, Fall 2023
An in depth introduction to genes, their sexual and asexual transmission in individuals and populations, and gene regulation in prokaryotes and eukaryotes. Gene manipulation by recombination, molecular cloning and genome editing is presented in contexts ranging from fundamental mechanisms of chromosome biology to applications in development, aging and disease. Human genetic variation and quantitative evaluation are illuminated. Non-Mendelian and epigenetic modes of inheritance of transposable elements, prions and chromatin states are paired with discussions of groundbreaking technology rewriting the rules of how the genome is analyzed, with attention to the ethical considerations ranging from the history of eugenics to modern controversies.
General Genetics: Read More [+]
Rules & Requirements
Prerequisites: Biology 1A and 1AL
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Terms offered: Spring 2024, Spring 2023, Spring 2022
Experimental techniques in classical and molecular genetics.
Genetics Laboratory: Read More [+]
Rules & Requirements
Prerequisites: Molecular and Cell Biology 104 or 140. May be taken concurrently
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture and 6 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Terms offered: Spring 2024, Spring 2023, Spring 2022
An introduction to principles and processes of embryonic and post-embryonic development, stressing mechanisms of cell and tissue interactions, morphogenesis and regulation of gene expression.
Developmental Biology: Read More [+]
Rules & Requirements
Prerequisites: 102 or C100A; Biology 1A, 1AL, and 1B; 110 or 130 recommended
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Formerly known as: 131
Terms offered: Fall 2023, Fall 2016, Fall 2015
This course is intended for upper-division undergraduates seeking an interactive course based on modern concepts in evolution and comparative genomics. The course will emphasize the contribution of molecular evolution to a series of seminal events in life's history: origin of life; origin of cells; origin of eukaryotes; origin of multicellularity; evolution of animal development; human origins.
Evolution of Genomes, Cells, and Development: Read More [+]
Rules & Requirements
Prerequisites: Biology 1A-1B and Molecular and Cell Biology C100A or 102; 104 or 140 recommended
Credit Restrictions: Student will receive no credit for 143 after taking Integrative Biology 163.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructor: King
Terms offered: Fall 2024, Fall 2023
An analysis of the patterns and processes of organic evolution. History and philosophy of evolutionary thought; the different lines of evidence and fields of inquiry that bear on the understanding of evolution. The major features and processes of evolution through geologic times; the generation of new forms and new lineages; extinction; population processes of selection, adaptation, and other forces; genetics, genomics, and the molecular basis of evolution; evolutionary developmental biology; sexual selection; behavorial evolution; applications of evolutionary biology to medical, agricultural, conservational, and anthropological research.
Evolution: Read More [+]
Rules & Requirements
Credit Restrictions: Students will receive no credit for INTEGBI 160 after completing ZOOLOGY 109.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructor: Whiteman
Formerly known as: Integrative Biology 160
Also listed as: INTEGBI C160
Terms offered: Spring 2024, Fall 2022, Spring 2007, Spring 2005
Biology has become a data science! This lab course aims for student curiosity to drive hands-on
case studies and coding projects about biological applications of data science. The course design
supports students’ development of fundamental and transferable computational and statistical
skills for critically thinking about and using data in biology. Ethical considerations are
interwoven throughout. This course offers projects with multiple levels of sophistication and
complexity, enabling participation for students with varying levels of experience.
Data Science for Biology: Read More [+]
Objectives & Outcomes
Course Objectives: Students will become empowered to use basic coding approaches to access, work with, and
analyze biological data
Students will learn how to appropriately apply statistical tests to biological data
Students will learn how to select and evaluate methods and tools for data analysis
Students will understand how to grapple with the ethical considerations of biological data
Rules & Requirements
Prerequisites: Biology 1A; Biology 1B (can be taken concurrently); Data C8 or equivalent statistics and programming experience
Hours & Format
Fall and/or spring: 15 weeks - 4 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Alternate method of final assessment during regularly scheduled final exam group (e.g., presentation, final project, etc.).
Instructors: Brenner, Eisen
Also listed as: BIO ENG C146/PLANTBI C146
Terms offered: Spring 2024, Spring 2023, Spring 2022
Course emphasizes bacterial and archaeal genetics and comparative genomics. Genetics and genomic methods used to dissect metabolic and development processes in bacteria, archaea, and selected microbial eukaryotes. Genetic mechanisms integrated with genomic information to address integration and diversity of microbial processes. Introduction to the use of computational tools for a comparative analysis of microbial genomes and determining relationships among bacteria, archaea, and microbial eukaryotes.
Microbial Genomics and Genetics: Read More [+]
Rules & Requirements
Prerequisites: Molecular and Cell Biology C100A/Chemistry C130 or Molecular and Cell Biology 102
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Summer:
8 weeks - 6 hours of lecture and 2 hours of discussion per week
10 weeks - 5 hours of lecture and 1.5 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Brenner, Taga
Also listed as: PLANTBI C148
Terms offered: Fall 2024, Fall 2023, Fall 2022
This is an upper division course for majors in MCB with an interest in an in-depth exploration of the forces that shape the human genome and the human population, as well as the ways that human genetic information can be used in medicine, ancestry and forensics. The course will combine lectures and discussion of research papers.
The Human Genome: Read More [+]
Rules & Requirements
Prerequisites: MCELLBI 110 and MCELLBI 140, MCELLBI 104 or equivalent
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Alternative to final exam.
Instructors: Eisen, Meyer, Rokhsar
Terms offered: Fall 2024, Spring 2024, Fall 2023
Fundamentals of immunology with emphasis on biochemical and molecular approaches to study of the immune system and its application in medicine and biotechnology. Topics covered include description of the immune system, antibody and T-cell receptor structure and function, genes of the immunoglobulin superfamily, cells and molecular mediators that regulate the immune response, allergy, autoimmunity, immunodeficiency, tissue and organ transplants, and tumor immunology.
Molecular Immunology: Read More [+]
Rules & Requirements
Prerequisites: C100A/Chemistry C130, or 102
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Terms offered: Fall 2024, Spring 2024, Fall 2023
Experimental techniques in mammalian molecular biology and cellular immunology. Molecular techniques covered include PCR and recombinant DNA procedures such as gene cloning, gene transfer, DNA sequencing, Southern blot, and restriction mapping. Immunological techniques covered include cell culture and monoclonal antibody production, flow cytometry, ELISA, immunoprecipitation, and western blot.
Immunology Laboratory: Read More [+]
Rules & Requirements
Prerequisites: Molecular and Cell Biology 150 (may be taken concurrently); consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 8 hours of laboratory and 1 hour of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Formerly known as: Microbiology 103L
Terms offered: Fall 2024, Fall 2023, Fall 2022
The overarching goal of MCB153 is to convey to students the scientific and regulatory process by which therapeutic drugs are developed and created. After completing this course, students will have a firm understanding on the mechanism of action of several therapies used to fight disease. The course will cover areas such as the discovery and refinement of antibiotics, anti-virals, cancer therapies and CRISPR-based therapies. Furthermore, MCB153 will delve into disease areas not covered in other courses, such as autoimmune diseases, cardiovascular diseases and neurological diseases. Lastly, MCB153 will implement a “case study” for each topic displaying real world challenges and solutions to treating complex diseases.
Molecular Medicine: Read More [+]
Rules & Requirements
Prerequisites: BIOLOGY 1A and MCELLBI 102, MCELLBI C100A, or CHEM 135
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Dillin, Stanley
Terms offered: Fall 2023, Fall 2022, Fall 2021
Comprehensive introductory survey of cellular and molecular neuroscience, including cellular neurophysiology, ion channel function, synaptic function and plasticity, sensory transduction, and brain development. Includes introduction to molecular basis of neurological disease. Analysis from the level of molecules to cells to simple circuits.
Cellular and Molecular Neurobiology: Read More [+]
Rules & Requirements
Prerequisites: Biology 1A and 1AL. Prerequisite or co-requisite: Physics 8B
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Formerly known as: Molecular and Cell Biology C160/Neuroscience C160
Terms offered: Fall 2023, Fall 2022, Fall 2021
Experimental analyses of properties and interactions of nerve cells and systems, illustrating principal features and current methods. Techniques employed include computer simulation of neuron properties, electrophysiological recording and stimulation of nerves and cells, digitally enhanced video imaging of outgrowth, fluorescence immunocytochemistry, analysis of sensory: CNS mapping, human-evoked potential recording, sensory psychophysics.
Neurobiology Laboratory: Read More [+]
Rules & Requirements
Prerequisites: Biology 1A, 1AL; Physics 8A, 8B; MCB 160 or equivalent (may be taken concurrently). Recommended: a course in physical chemistry
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture and 8 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Terms offered: Fall 2023, Fall 2022, Fall 2021
Electrochemistry and ion transport phenomena, equivalent circuits, excitability, action potentials, voltage clamp and the Hodgkin-Huxley model. Biophysical properties of ion channels. Statistical and electrophysiological models of synaptic transmission, Quantitative models for dendritic structure and neuronal morphogenesis. Sensory transduction, cellular networks as computational devices, information processing and transfer.
Biophysical Neurobiology: Read More [+]
Objectives & Outcomes
Course Objectives: 1)
Derive equations for Nernst and GHK membrane potential from fundamental physics concepts.
2)
Describe the experiments and theory underlying the Hodgkin-Huxley model.
3)
Understand biophysical properties of gating particles called ion channels.
4)
Apply and solve equivalent circuit models to describe resting and excitable cells, synaptic transmission and sensory transduction.
5)
Use Poisson, Gaussian and binomial distributions to analyze the gating of ion channels, synaptic transmission, and absolute sensitivity of vision.
6)
Model dendritic structure based on quantitative descriptors of shape and energy minimization theory.
7)
Explain experiments and models of sensory transduction, neuronal integration and lateral inhibition.
Rules & Requirements
Prerequisites: Biology 1A, 1AL, Physics 8A-8B, Chemistry 1A, 3A/3AL-3B, or consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Elul, Isacoff, Miller
Terms offered: Fall 1995
Sensory cells monitor the environment to trigger behaviors required to feed, avoid danger and thrive. This interactive course combines lectures with instructor-led discussions of research from the scientific literature. Our goals are two fold. First, we will present current concepts in sensory neurobiology by illustrating how different sensory inputs govern homeostasis and behavior. Second, though discussions of scientific data, the course will foster critical thinking skills, and provide practice in drawing logical, evidence-based conclusions.
Sensory Neuroscience: Read More [+]
Rules & Requirements
Prerequisites: MCELLBI 160 or BIOLOGY 1A/1AL-1B, PHYSICS 8A-8B and consent of Instructor
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam required.
Instructors: Lumpkin, Bautista
Terms offered: Summer 2024 First 6 Week Session, Summer 2023 First 6 Week Session, Summer 2022 First 6 Week Session
This laboratory course for majors in Chemical Biology, Cell Biology, and Biochemistry & Molecular Biology is designed to have students learn the theory and practicality of modern laboratory science. The first and last third of the course will focus on Molecular Biology and Biochemistry where the students will learn basic skills and investigate the role of Kinesin 5 in Mitosis. In the middle Cell Biology portion of the course you will learn about cell structure and the cytoskeleton with an emphasis on microscopy techniques.
Molecular and Cell Biology Laboratory: Read More [+]
Rules & Requirements
Prerequisites: MCELLBI 102, MCELLBI 104, MCELLBI 110 or MCELLBI 140
Credit Restrictions: Students will receive no credit for Molecular and Cell Biology 170L after taking Molecular and Cell Biology 133L, 140L or C110L/Chemistry C110L
Hours & Format
Summer: 6 weeks - 5 hours of lecture and 14 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Instructor: Le Blanc
Terms offered: Prior to 2007
Blended lecture / Project-based course where student teams build out a business plan for a mock biotech company, demonstrating advanced knowledge in therapeutics and business development. Throughout the course student teams will work toward a final project in which they will identify and present a technology overview, disease overview and explanation of unmet need, a development plan, a commercialization plan, risk mitigation strategy, and financials. Class will include field trips, guest lectures, and a pitch competition with prize.
Life Sciences, Business, and Entrepreneurship Capstone Course: Read More [+]
Rules & Requirements
Prerequisites: Students must be in their fourth and final year of the Life Sciences, Business, and Entrepreneurship Program in order to enroll in this class
Hours & Format
Fall and/or spring: 15 weeks - 4 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Alternative to final exam.
Instructors: Schaletzky, Dillin
Also listed as: UGBA C195C
Life Sciences, Business, and Entrepreneurship Capstone Course: Read Less [-]
Terms offered: Summer 2022 8 Week Session, Spring 2012, Spring 2007
Course consists of a weekly three-hour training session that focuses on laboratory techniques, instructional aids, and problem solving, plus an additional three hour weekly laboratory where the UGSI is required to assist a GSI in the instruction of laboratory (answering questions, providing demonstrations, etc.).
Undergraduate Teaching of Biology 1A Laboratory: Read More [+]
Rules & Requirements
Prerequisites: Biology 1A, 1AL with a minimum grade of B. Appointment as a UGSI in biology by consent of instructor. Restricted to undergraduate students
Repeat rules: Course may be repeated for credit up to a total of 4 units.
Hours & Format
Fall and/or spring: 15 weeks - 3-6 hours of session per week
Summer: 8 weeks - 6-12 hours of session per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
Undergraduate Teaching of Biology 1A Laboratory: Read Less [-]
Terms offered: Fall 2012, Fall 2011, Fall 2010
Course consists of a weekly three-hour training session that focuses on laboratory techniques, instructional aids, and problem solving, plus an additional three-hour weekly laboratory where the UGSI is required to assist a GSI in the instruction of laboratory (answering questions, providing demonstrations, etc.). Students will be graded on lecture and laboratory attendance and preparation of one quiz.
Undergraduate Teaching of Molecular and Cell Biology 32 Laboratory: Read More [+]
Rules & Requirements
Prerequisites: 32, 136, or Integrative Biology 132 and Molecular and Cell Biology 32L or Integrative Biology 132L laboratory courses in physiology with minimum grades of B. Appointment as a UGSI in physiology by consent of instructor
Repeat rules: Course may be repeated for credit up to a total of 4 units.
Hours & Format
Fall and/or spring: 15 weeks - 3-6 hours of session per week
Summer:
6 weeks - 7.5-15 hours of session per week
8 weeks - 5.5-11 hours of session per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam required.
Undergraduate Teaching of Molecular and Cell Biology 32 Laboratory: Read Less [-]
Terms offered: Summer 2024 3 Week Session, Summer 2023 3 Week Session, Summer 2022 3 Week Session
This 3 week course will address topics in genome editing and CRISPR-Cas9 research, including basic and enhanced CRISPR methods, cellular repair mechanisms, regulation of gene expression, bioinformatics, applications to various organisms, and bioethics. Students will learn from a collection of local experts about ongoing campus research, and gain the background knowledge to understand current publications and applications of genome editing.
Intro to CRISPR: From Basic Biology to Genome Editing Technology: Read More [+]
Rules & Requirements
Prerequisites: BIOLOGY 1A or equivalent
Hours & Format
Summer: 3 weeks - 4 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam required.
Instructors: Hockemeyer, Wilson
Intro to CRISPR: From Basic Biology to Genome Editing Technology: Read Less [-]
Terms offered: Summer 2019 3 Week Session
This 3 week lab course will focus on applications of CRISPR technology as a platform for genome editing and functional genomics. The program will consist of a hands-on laboratory experience demonstrating how CRISPR systems work in situ, as well as use genome editing both in vitro and in vivo. Students will utilize fundamental molecular biology techniques and learn additional protocols specific to genome editing. Two bioinformatics based lessons will cover the essential programs and analyses used in the genome editing field. This course requires concurrent enrollment in a lecture component (MCELLBI N184), where lecturers will address topics in genome editing and CRISPR-Cas9 research.
Intro to CRISPR Lab: From Basic Biology to Genome Editing Technology: Read More [+]
Rules & Requirements
Prerequisites: Biology 1A/1AL or equivalent course. MCELLBI N184 (may be taken concurrently)
Hours & Format
Summer: 3 weeks - 14 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
Instructors: Hockemeyer, Wilson
Intro to CRISPR Lab: From Basic Biology to Genome Editing Technology: Read Less [-]
Terms offered: Spring 2021, Spring 2020
This course is intended for advanced undergraduates wishing to pursue independent research projects under the mentorship of an Molecular and Cell Biology faculty member. To apply for MCELLBI 191, the research project must be rigorous and provide significant training in biology.
Senior Research Thesis: Read More [+]
Rules & Requirements
Prerequisites: Consent of instructor and departmental adviser
Credit Restrictions: Students will receive no credit for MCELLBI 191 after completing MCELLBI H196B, or MCELLBI H196A.
Hours & Format
Fall and/or spring: 15 weeks - 9 hours of independent study per week
Summer:
6 weeks - 23 hours of independent study per week
8 weeks - 17 hours of independent study per week
10 weeks - 14 hours of independent study per week
12 weeks - 12 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Alternative to final exam.
Terms offered: Fall 2018, Fall 2017
UGSIs will work under supervision of instructor and/or GSI. The UGSI will attend three hours of lecture per week where they will assist a GSI in instruction (answering questions, providing demonstrations, facilitating activities, etc.). In addition, UGSIs will meet with students from their section for zero to three hours of tutoring per week depending on the number of units. UGSIs do not evaluate students' work or assign grades. UGSIs will be graded on attendance and preparation of one lesson plan and one quiz. Required to attend any mandatory preparatory and review meetings.
Undergraduate Student Instructor for Molecular and Cell Biology Courses: Read More [+]
Rules & Requirements
Prerequisites: Must have completed course applying to UGSI with a grade of B or better; or consent of instructor
Repeat rules: Course may be repeated for credit up to a total of 4 units.
Hours & Format
Fall and/or spring: 15 weeks - 3-3 hours of lecture per week
Summer: 8 weeks - 6-6 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Alternative to final exam.
Undergraduate Student Instructor for Molecular and Cell Biology Courses: Read Less [-]
Terms offered: Fall 2015, Fall 2014, Spring 2014
Individual research and thesis preparation under the supervision of a faculty member. Acceptance to the Molecular and Cell Biology Honors Program is required. Contact the MCB Undergraduate Affairs Office, 3060 Valley Life Sciences Building, for application and details. Honor students must complete at least two semesters of research, taking a minimum of 4 units and a maximum of 8 units of H196A-196B. If desired, one semester of 199 can be used to replace H196A.
Honors Research: Read More [+]
Rules & Requirements
Prerequisites: Senior honors status and consent of instructor
Repeat rules: Course may be repeated for credit up to a total of 4 units.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of independent study per week
Summer: 8 weeks - 1.5-7.5 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
Terms offered: Spring 2020, Spring 2016, Spring 2015
Individual research and completion of thesis under the supervision of a faculty member. This course satisfies the thesis requirement for the Molecular and Cell Biology Department Honors Program. Contact the MCB Undergraduate Affairs Office, 3060 Valley Life Sciences Building, for program details and an application. Honor students must complete at least two semesters of research, taking a minimum of 4 units and a maximum of 8 units of H196A-196B. One semester of H196B is required.
Honors Research: Read More [+]
Rules & Requirements
Prerequisites: Senior honors status and consent of instructor
Repeat rules: Course may be repeated for credit up to a total of 4 units.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of independent study per week
Summer: 8 weeks - 1.5-7.5 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Letter grade. Final exam not required.
Terms offered: Fall 2016
Supervised experience relevant to specific topics of biology in off-campus organizations. Written report and evaluation from internship supervisor required.
Supervised Internship: Read More [+]
Rules & Requirements
Prerequisites: Consent of MCB Faculty, restricted to MCB majors and prospective majors only. Certification from supervisor that credit is required
Repeat rules: Course may be repeated for credit with instructor consent.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of internship per week
Summer: 6 weeks - 8 hours of internship per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
Terms offered: Spring 2024, Fall 2023, Spring 2023
Lectures and small group discussions focusing on topics of interest, varying from semester to semester.
Directed Group Study: Read More [+]
Rules & Requirements
Prerequisites: Upper division standing
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of directed group study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
Terms offered: Fall 2023, Fall 2020, Spring 2020
Enrollment restrictions apply; see the Introduction to Courses and Curricula section of this catalog.
Supervised Independent Study and Research: Read More [+]
Rules & Requirements
Prerequisites: Consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of independent study per week
Summer:
6 weeks - 1-4 hours of independent study per week
8 weeks - 1-4 hours of independent study per week
10 weeks - 1-4 hours of independent study per week
12 weeks - 1-4 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Undergraduate
Grading/Final exam status: Offered for pass/not pass grade only. Final exam not required.
Terms offered: Fall 2024, Fall 2023, Fall 2022
The goal of this course is to provide graduate-level instruction on molecular and cellular biosciences from a highly-integrated systems perspective, rather than using a more classic, techniques-oriented format. A collection of approaches, and a focus on critical thinking and problem solving, will be used to show how fundamental, highly-significant biological problems are "cracked open." Reading will be assigned from a mix of classic and current peer-reviewed papers selected by the instructors.
Fundamentals of Molecular and Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: 200A and 200B must be taken concurrently. Combined course required and restricted to all MCB first-year graduate students
Hours & Format
Fall and/or spring: 15 weeks - 6 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructors: Marqusee, Rio, Drubin, Rine, Vance, Feller
Terms offered: Fall 2024, Fall 2023, Fall 2022
The goal of this course is to provide graduate-level instruction on molecular and cellular biosciences from a highly-integrated systems perspective, rather than using a more classic, techniques-oriented format. A collection of approaches, and a focus on critical thinking and problem solving, will be used to show how fundamental, highly-significant biological problems are "cracked open." Reading will be assigned from a mix of classic and current peer-reviewed papers selected by the instructors.
Fundamentals of Molecular and Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: Must be taken concurrently. Combined course required for all MCB first-year graduate students
Hours & Format
Fall and/or spring: 15 weeks - 6 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructors: Marqusee, Rio, Drubin, Rine, Vance, Feller
Terms offered: Summer 2024 Second 6 Week Session
This course seeks to develop students’ foundation in critical lab skills and introduce them to the fundamental principles and technologies driving modern biomedical research. After completing MCELLBI 201A, students will have a firm understanding of CRISPR gene editing, cell culture, and genomic analysis. Students will learn the fundamentals of hypothesis-driven research, obtain critical thinking skills for data interpretation, and deliver effective written and oral reports of their results.
CRISPR Gene Editing, Stem Cell and Genomic Analysis: Read More [+]
Rules & Requirements
Prerequisites: BIOLOGY 1A and MCELLBI 102 or equivalent courses
Credit Restrictions: Students will receive no credit for MCELLBI 201A after completing MCELLBI 201A. A deficient grade in MCELLBI 201A may be removed by taking MCELLBI 201A.
Hours & Format
Summer: 6 weeks - 4 hours of lecture and 18 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructors: He, Luo
CRISPR Gene Editing, Stem Cell and Genomic Analysis: Read Less [-]
Terms offered: Fall 2024
This course seeks to build upon students’ foundations set in MCELLBI 201A, in which they were introduced to the fundamental principles and technologies driving modern biomedical research. MCELLBI 201B aims to develop students’ skills in bioinformatics and quantitative data analysis. After completing this course, students will understand the RNA-Seq and ChIP-Seq pipelines and carry out their own analyses. Students will continue to learn the fundamentals of experimental design, obtain critical thinking skills for data interpretation, and deliver effective presentations on their results.
CRISPR Gene Editing, Stem Cell and Genomic Analysis: Read More [+]
Rules & Requirements
Prerequisites: MCELLBI 201A
Credit Restrictions: Students will receive no credit for MCELLBI 201B after completing MCELLBI 201B. A deficient grade in MCELLBI 201B may be removed by taking MCELLBI 201B.
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture and 9 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructor: Ingolia
CRISPR Gene Editing, Stem Cell and Genomic Analysis: Read Less [-]
Terms offered: Fall 2024, Fall 2023, Spring 2023
This course is intended for graduate students in the early stages of their thesis research who are contemplating using modern microscopy tools as part of their work. It endeavors to cut through the confusion of the wide array of new imaging methods, with a practical description of the pros and cons of each. In addition to providing an intuitive physical understanding how these microscopes work, the course will offer hands on experience with cutting-edge microscopes where students will be able to see firsthand how different imaging modalities perform on their own samples, and where they will be able to access computational tools for the visualization and analysis of their data.
Modern Optical Microscopy for the Modern Biologist: Read More [+]
Rules & Requirements
Credit Restrictions: Students will receive no credit for MCELLBI 205 after completing MCELLBI 205, or MCELLBI 205. A deficient grade in MCELLBI 205 may be removed by taking MCELLBI 205, or MCELLBI 205.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructors: Betzig, Ji
Formerly known as: Molecular and Cell Biology 205
Also listed as: NEU C272/PHYSICS C218
Modern Optical Microscopy for the Modern Biologist: Read Less [-]
Terms offered: Spring 2024, Spring 2023, Spring 2022
Application of modern physical concepts and experimental methods to the analysis of the structure, function, and interaction of large molecules of biological interest.
Physical Biochemistry: Read More [+]
Rules & Requirements
Prerequisites: MCB C100A or equivalent. Admission to the course requires formal consent of instructors, except for MCB and Biophysics graduate students and graduate students in the laboratories of MCB faculty
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Terms offered: Spring 2024, Spring 2023, Spring 2022
General course for first-year graduate students. Covers our current understanding of, methodological approaches for analyzing, and recent advances in the function of cellular macromolecules and macromolecular complexes in DNA replication, recombination, transposition and repair, gene expression and its regulation, mRNA splicing, genome organization, noncoding RNAs, signal transduction, protein synthesis, folding and degradation, growth control, and other life processes.
Advanced Biochemistry and Molecular Biology: Macromolecular Reactions and the Cell: Read More [+]
Rules & Requirements
Prerequisites: 110 or equivalent. Admission to the course requires formal consent of instructors, except for MCB graduate students and graduate students in the laboratories of MCB faculty
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Formerly known as: 200
Advanced Biochemistry and Molecular Biology: Macromolecular Reactions and the Cell: Read Less [-]
Terms offered: Spring 2024, Spring 2023, Spring 2022
This course will present the structure of proteins, nucleic acids, and oligosaccharides from the perspective of organic chemistry. Modern methods for the synthesis and purification of these molecules will also be presented.
Chemical Biology I - Structure, Synthesis and Function of Biomolecules: Read More [+]
Hours & Format
Fall and/or spring: 5 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Also listed as: CHEM C271A
Chemical Biology I - Structure, Synthesis and Function of Biomolecules: Read Less [-]
Terms offered: Spring 2024, Spring 2023, Spring 2022
This course will focus on the principles of enzyme catalysis. The course will begin with an introduction of the general concepts of enzyme catalysis which will be followed by detailed examples that will examine the chemistry behind the reactions and the three-dimensional structures that carry out the transformations.
Chemical Biology II - Enzyme Reaction Mechanisms: Read More [+]
Hours & Format
Fall and/or spring: 5 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Also listed as: CHEM C271B
Chemical Biology II - Enzyme Reaction Mechanisms: Read Less [-]
Terms offered: Spring 2024, Spring 2023, Spring 2022
This course will build on the principles discussed in Chemical Biology I and II. The focus will consist of case studies where rigorous chemical approaches have been brought to bear on biological questions. Potential subject areas will include signal transduction, photosynthesis, immunology, virology, and cancer. For each topic, the appropriate bioanalytical techniques will be emphasized.
Chemical Biology III - Contemporary Topics in Chemical Biology: Read More [+]
Hours & Format
Fall and/or spring: 5 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Also listed as: CHEM C271C
Chemical Biology III - Contemporary Topics in Chemical Biology: Read Less [-]
Terms offered: Spring 2020, Spring 2015, Spring 2014, Spring 2013
The topics covered will be chosen from the following: protein structure; protein-protein interactions; enzyme kinetics and mechanism; enzyme design. Intended for graduate students in chemistry, biochemistry, and molecular and cell biology.
Protein Chemistry, Enzymology, and Bio-organic Chemistry: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing or consent of instructor
Hours & Format
Fall and/or spring:
10 weeks - 3 hours of lecture per week
15 weeks - 2 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Also listed as: CHEM C230
Protein Chemistry, Enzymology, and Bio-organic Chemistry: Read Less [-]
Terms offered: Fall 2024, Fall 2022, Fall 2021, Fall 2020
This workshop for graduate students will parallel C116, Microbial Diversity, which should be taken concurrently. Emphasis in the workshop will be on review of research literature and formulation of paper pertinent to research in microbial diversity.
Microbial Diversity Workshop: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing; C112 or consent of instructor and organic chemistry (may be taken concurrently)
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of workshop and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructor: Coates
Formerly known as: Molecular and Cell Biology C216, Plant and Microbial Biology C216
Also listed as: PLANTBI C216
Terms offered: Fall 2024, Spring 2024, Fall 2023
Biochemistry of Cu, Fe, Zn and Mn homeostasis and comparative genomics of algae, especially related to photosynthesis and chloroplast biology. Mechanisms of elemental
sparing, including responses to N, S, and P deficiency.
Research Review in Biochemistry and Molecular Biology: Trace Elements in the Plant Lineage: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Merchant
Terms offered: Spring 2024, Fall 2023, Spring 2023
Synthetic biology, metabolic engineering, systems biology, enzyme mechanism, and gene discovery.
Research Review in Biochemistry and Molecular Biology: Synthetic Biology and Cellular Enzymology: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor or consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Chang
Terms offered: Fall 2024, Spring 2024, Fall 2023
Our goals are to decipher the fundamental principles that govern substrate engagement, de-ubiquitylation, unfolding, and translocation by the proteasome.
Research Review in Biochemistry and Molecular Biology: Energy-dependent Proteases and Molecular Machines: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor or consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Martin
Terms offered: Fall 2024, Spring 2024, Fall 2023
The mechanism of protein synthesis in bacteria and human cells. Specific areas of interest include the structure and function of the ribosome and the regulation of protein synthesis.
Research Review in Biochemistry and Molecular Biology: Protein Synthesis in Bacteria and Mammals: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Cate
Terms offered: Spring 2024, Fall 2023, Spring 2023
Research and literature topics in chemical biology and inorganic chemistry relevant to human health and disease and energy science will be discussed.
Research Review in Biochemistry and Molecular Biology: Chemical Biology and Inorganic Chemistry: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Chris Chang
Terms offered: Fall 2022, Fall 2021, Spring 2021
Transduction of cellular sequences and genetic regulation of transformation by oncogenic retroviruses as models for natural carcinogenesis, including a critical review of the current research.
Research Review in Biochemistry and Molecular Biology: Advanced 20th Century Perspectives on Cancer Cell Genetics: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Duesberg
Terms offered: Fall 2024, Spring 2024, Fall 2023
In our laboratory, we study mechanisms by which molecules are transported across lipid bilayer membranes. Current research efforts to understand mechanisms of protein translocation across intracellular organelles and transport of other biomolecules will be discussed.
Research Review in Molecular Mechanisms of Membrane Transport: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Park
Research Review in Molecular Mechanisms of Membrane Transport: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Topics at the interface of chemistry and biology with a particular focus on mechanisms of enzyme catalysis.
Research Review in Biochemistry and Molecular Biology: Chemical Biology and Enzymology: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Marletta
Terms offered: Fall 2024, Spring 2024, Fall 2023
Molecular approaches to designing and deploying tools for voltage imaging and brain mapping.
Research Review in Biochemistry and Molecular Biology: Chemical Biology and Neuroscience: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructors: Miller, Evan
Terms offered: Fall 2024, Spring 2024, Fall 2023
Yildiz laboratory combines molecular biology and single molecule biophysical techniques to understand mechanisms that underlie cellular organization and motility. Specific focuses of the lab are to dissect 1) the mechanism of cytoplasmic dynein motility, 2) the regulation of intraflagellar transport, and 3) the protection and maintenance of mammalian telomeres.
Research Review in Biochemistry and Molecular Biology: Single Molecular Imaging of Macromolecular Enzymes: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Yildiz
Terms offered: Fall 2024, Spring 2024, Fall 2023
Structure-function studies of the cytoskeleton and large molecular machines by cryo-electron microscopy and image reconstruction.
Research Review in Biochemistry and Molecular Biology: Cryo-Electron Microscopy of Macromolecules: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Nogales
Terms offered: Spring 2023, Fall 2022, Spring 2022
Different methods for determining how the in situ structure and arrangement of macromolecular complexes influence cell morphology and
function will be discussed via literature review and implemented through lab-based research and discussions.
Electron Cryo-tomography of Macromolecular Complexes: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Davies
Electron Cryo-tomography of Macromolecular Complexes: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Discussion of recent advances in the mechanism of epigenetic modifications on mammalian gene regulation and developing tools for precision editing of epigenetic modifications for controlling gene expression.
Research Review in Biochemistry and Molecular Biology: Epigenetic Gene Regulation: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Nunez
Research Review in Biochemistry and Molecular Biology: Epigenetic Gene Regulation: Read Less [-]
Terms offered: Fall 2014, Spring 2014, Fall 2013
Review of current literature and discussion of original research.
Research Review in Biochemistry and Molecular Biology: Biophysics of Macromolecule Transport Across Membranes: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Krantz
Terms offered: Fall 2024, Spring 2024, Fall 2023
Define how metabolic reactions function in the context of the cellular system in order to elucidate the so-called design principles of metabolic function.
Research Review in Biochemistry and Molecular Biology: Chemical Reactions of Metabolism: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Savage
Terms offered: Fall 2024, Spring 2024, Fall 2023
The mechanisms by which protein complexes use their structures to bud, bend, and sever membranes will be covered in research reports and reviews of the current literature and in discussion of current experiments in the field.
Structural Membrane Biology: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Hurley
Terms offered: Fall 2024, Spring 2024, Fall 2023
Understanding the molecular basis and physiological role of translational regulation in gene expression with an emphasis on global profiling and functional genomics.
Regulation of Translation: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Ingolia
Terms offered: Fall 2024, Spring 2024, Fall 2023
Discussion of recent research on the genetics, cell biology, and immunology of the model facultative intracellular bacterical pathogen,
Research Review in Biochemistry and Molecular Biology: Molecular and Cell Biology of Listeria monocytogenes Pathogenesis: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Portnoy
Terms offered: Spring 2021, Spring 2002, Fall 2001
Discussion of recent research on chemical biology, synthetic biology, organic chemistry and biophysics.
Research Review in Chemical Biology, Synthetic Biology, Organic Chemistry and Biophysics: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Schepartz
Terms offered: Spring 2024, Fall 2023, Spring 2023
Mechanisms and structure in DNA replication and eukaryotic cell signaling.
Research Review in Biochemistry and Molecular Biology: Structural Biology of Signaling and Replication: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Kuriyan
Terms offered: Fall 2024, Spring 2024, Fall 2023
Methods of single molecule manipulation and visualization that are used to characterize the structure and mechanochemical properties of translocating DNA binding protein such as RNA polymerase and to investigate the mechanical denaturation of single protein molecules will be covered in research reports and reviews of the current literature and in discussion of current experiments in the field.
Research Review in Biochemistry and Molecular Biology: Single Molecule Biophysics: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Bustamante
Research Review in Biochemistry and Molecular Biology: Single Molecule Biophysics: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Regulation of HIV gene expression by viral proteins and cellular cofactors will be covered in research reports and reviews of the current literature and in discussion of current experiments in the field.
Research Review in Biochemistry and Molecular Biology: Regulation of HIV Gene Expression: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Zhou
Terms offered: Fall 2024, Spring 2024, Fall 2023
Emphasizes eukaryotic retroelement reverse transcriptases and retroelement mobility.
Research Review in Biochemistry and Molecular Biology: Polymerase and RNA Biochemistry and Biology: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Collins
Terms offered: Spring 2024
This class is designed to introduce graduate students to a range of therapeutic modalities that are in development or use. It will focus on small molecules, genomic therapies (including genome editing), and biologics. This class will present different applications of small molecules, RNA or DNA therapeutics, and biologics and discuss both advantages and challenges in their clinical use.
Therapeutic Modalities: Read More [+]
Rules & Requirements
Prerequisites: For MCB students, MCELLBI 200A and MCELLBI 200B are prerequisites for this class. Students outside of MCB should check with the head instructor whether they have the required background to follow this class most productively
Credit Restrictions: Students will receive no credit for MCELLBI 220 after completing MCELLBI 220. A deficient grade in MCELLBI 220 may be removed by taking MCELLBI 220.
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructor: Olzmann
Terms offered: Fall 2024
The overarching goal of this course is to provide students with professional skills in scientific reading, scientific writing, creating a CV or resume and cover letters and understanding the structures of academic institutions and biotech companies. In addition, the class will provide career advice for students entering the academic or biotech work places.
Science Writing and Professional Development: Read More [+]
Rules & Requirements
Prerequisites: This course will be limited to students enrolled in the MCB Master of Biotechnology program
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructor: Beatty
Terms offered: Fall 2024, Spring 2024, Fall 2023
Recent developments in eukaryote viral and cellular regulation. New concepts in transcription and RNA replication, with particular emphasis on virus-cell interactions.
Research Review in Viruses as Models for Eukaryote Gene Expression and Replication: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor or consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Botchan
Formerly known as: Molecular and Cell Biology 218E
Research Review in Viruses as Models for Eukaryote Gene Expression and Replication: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Research review in genetics, genomics and development. We will explore how the detection of single particles
(DNA, RNA, proteins) can help with understanding cellular organization and
enzymatic processes dynamics and kinetics. Most of the experiments
described will be drawn from the gene expression and nuclear organization
literature.
Research Review in Molecular Therapeutics: Imaging Single Molecules: Fashion or Game Changer?: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Darzacq
Formerly known as: Molecular and Cell Biology 249L
Terms offered: Fall 2024, Spring 2024, Fall 2023
RNA structure, folding, and function. Specific topics include ribozyme mechanisms, RNA-mediated translation initiation, and protein targeting and secretion.
Research Review in Molecular Therapeutics: Structure and Function of RNA: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Doudna
Formerly known as: Molecular and Cell Biology 219J
Research Review in Molecular Therapeutics: Structure and Function of RNA: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Evaluation of current research in molecular mechanisms underlying diseases of the retina.
Research Review in Molecular Therapeutics: Diseases/Retina: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Flannery
Formerly known as: Molecular and Cell Biology 269U
Research Review in Molecular Therapeutics: Diseases/Retina: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Protein structure, stability, design, and the pathway of protein folding.
Research Review in Molecular Therapeutics: The Protein Folding Problem: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Marqusee
Formerly known as: Molecular and Cell Biology 218R
Research Review in Molecular Therapeutics: The Protein Folding Problem: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Understanding the creative strategies viruses use to manipulate gene expression in host cells, with a focus on RNA-based regulation of gene expression.
Research Review in Molecular Therapeutics: Virus-Host Interactions: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Glaunsinger
Formerly known as: Molecular and Cell Biology 219G
Research Review in Molecular Therapeutics: Virus-Host Interactions: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
We will discuss current research in the following three areas: 1) mapping metabolic drivers of human diseases using
chemoproteomic and metabolomic platforms; 2) expanding the druggable proteome through mapping and pharmacologically interrogating proteome-wide
hyper-reactive and ligandable hotspots; 3) mapping proteome-wide targets of environmental and pharmaceutical chemicals towards understanding novel
toxicological mechanisms.
Mapping Metabolic Drivers of Disease using Chemoproteomic and Metabolomic Platforms: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Nomura
Formerly known as: Molecular and Cell Biology 218A
Mapping Metabolic Drivers of Disease using Chemoproteomic and Metabolomic Platforms: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Discussion of recent literature and original research. Current research examines the cell biology of lipid homeostasis, including the mechanisms that regulate lipid droplet biogenesis, oxidative lipid damage, and ferroptosis.
Research Review in Molecular Therapeutics: Mechanisms of lipid homeostasis and lipotoxicity: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Olzmann
Formerly known as: Molecular and Cell Biology 239A
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of current literature and discussion of original research.
Research Review in Molecular Therapeutics: Regulation of the Cell Cycle: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Rape
Formerly known as: Molecular and Cell Biology 239B
Research Review in Molecular Therapeutics: Regulation of the Cell Cycle: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Covers aspects of ribosome engineering, organelle imaging and interactions, protein delivery, and cell signaling.
Research Review in Understanding and Exploiting Complex Biological Processes and Machines: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Schepartz
Formerly known as: Molecular and Cell Biology 218N
Terms offered: Fall 2024, Spring 2024, Fall 2023
Protein-DNA interactions and the control of gene expression in eukaryotes.
Research Review in Molecular Therapeutics: Eukaryotic Gene Expression: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Tjian
Formerly known as: Molecular and Cell Biology 219F
Research Review in Molecular Therapeutics: Eukaryotic Gene Expression: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Research focuses on (i) understanding the interplay between regulatory information encoded in the primary sequence of the human genome and epigenomic information inscribed by the joint action of trans-acting factors, chromatin remodelers, modifiers, and readers that yields a particular functional state in primary cells of the immune and central nervous systems; (ii) leveraging this understanding to engineer novel architectures for targeted epigenome editors customized for use in these and other clinically relevant human cell types; (iii) establishing preclinical proof-of-concept for the use of the resulting epigenome-editing molecular therapeutics in ex vivo and in vivo models of autoimmune and neurologic disease.
Research Review in Molecular Therapeutics: Structure and Function of the Human Epigenome: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Urnov
Formerly known as: Molecular and Cell Biology 249AA
Terms offered: Fall 2024, Spring 2024, Fall 2023
The molecular engineering of novel delivery technology to facilitate therapeutic genome editing. Delivery of pre-formed CRISPR ribonucleoprotein enzymes is a central focus, and progress in the field will be covered via research presentations as well as reviews of recent literature.
Research Review in Molecular Therapeutics: CRISPR Enzyme Delivery Technology: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Wilson
Formerly known as: Molecular and Cell Biology 218G
Research Review in Molecular Therapeutics: CRISPR Enzyme Delivery Technology: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
In our laboratory, we study the molecular mechanisms of nutrient sensing and growth control. Specific areas of interest include the mTOR pathway, energy sensing, lysosomal biology and translational control.
Research Review in Molecular Therapeutics: Molecular and Cellular Mechanisms of Nutrient Sensing: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Zoncu
Formerly known as: Molecular and Cell Biology 218Z
Terms offered: Spring 2024, Spring 2023, Spring 2022
This course will discuss modern concepts of cell and developmental biology, with a strong emphasis on regulatory mechanisms at different length-scales (intermolecular, intracellular and intercellular). It will cover methods of quantitative, single-cell, and organismal biology in cell lines, stem cells, and model organisms. A solid foundation of core cell biology concepts, such as the cell cycle, cytoskeleton, or vesicle transport, is strongly recommended.
Advanced Cell and Developmental Biology: Read More [+]
Rules & Requirements
Prerequisites: 130. Formal consent of instructors required, except for MCB graduate students and graduate students in the laboratories of MCB faculty
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Terms offered: Spring 2018, Spring 2017, Spring 2015
Principles of animal development will be set forth from the classical and recent experimental analysis of induction, localization, patterning mutants, axis formation, regional gene expression, and cell interactions. Early development of selected vertebrates and invertebrates will be examined, and emerging topics in microRNA and stem cell biology will be highlighted. A weekly discussion section with readings from the research literature is required.
Advanced Developmental and Stem Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: Previous course in development (131 or equivalent) or consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1-2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Terms offered: Fall 2024, Fall 2023, Fall 2022
Principles of mammalian (primarily human) physiology emphasizing physical, chemical, molecular, and cellular bases of functional biology. The following topics will be covered: cellular and membrane ion and nonelectrolyte transport; cell and endocrine regulation; autonomic nervous system regulation; skeletal, smooth, and cardiac muscle; cardiovascular physiology; respiration; renal physiology; gastrointestinal physiology. Discussion section will study advanced physiological topics, including: presentations by the faculty; problem sets; discussion of the primary literature and of reviews; two presentations by each student on topics in current physiological research.
Advanced Mammalian Physiology: Read More [+]
Rules & Requirements
Prerequisites: Consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 2 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Terms offered: Spring 2015, Spring 2014, Spring 2013
This course will provide an overview of basic and applied embryonic stem cell (ESC) biology. Topics will include early embryonic development, ESC laboratory methods, biomaterials for directed differentiation and other stem cell manipulations, and clinical uses of stem cells.
Stem Cells and Directed Organogenesis: Read More [+]
Rules & Requirements
Prerequisites: Consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 6 hours of laboratory and 1 hour of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructor: Conboy
Also listed as: BIO ENG C218
Terms offered: Spring 2024, Spring 2022, Spring 2020
Biology is being revolutionized by new experimental techniques that have made it possible to measure the inner workings of molecules, cells and multicellular organisms with unprecedented precision. The objective of this course is to explore this deluge of quantitative data through the use of biological numeracy. We will develop theoretical models that make precise predictions about biological phenomena. These predictions will be tested through the hands-on analysis of experimental data and by performing numerical simulations using Matlab. A laptop is required for this course, but no previous programming experience is required.
Advanced Physical Biology of the Cell: Read More [+]
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of laboratory per week
Summer: 8 weeks - 6 hours of lecture and 2 hours of laboratory per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructor: Garcia
Terms offered: Fall 2023, Fall 2022
This lecture series will cover modern approaches to stem cell biology, regenerative medicine and gene therapy. Lectures will include a broad introduction to the day’s topic, followed by in depth discussion of one specific recent example- preferably from the speaker’s own laboratory-that addresses an imminent question in the field. Relevant research articles will be assigned as background reading. Students are expected to become thoroughly familiar with these materials prior to each class meeting.
Stem Cell Research and Gene Therapy: Questions, Solutions and Current Frontiers: Read More [+]
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Hockemeyer
Stem Cell Research and Gene Therapy: Questions, Solutions and Current Frontiers: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Research in our laboratory is focused on the mechanics and dynamics of cell movements on the purified protein, single cell, and tissue levels. For these studies, we are developing new instruments to quantify cell and molecular mechanics bases on optical microscopy, force microscopy, and microfabrication.
Research Review in Cell and Developmental Biology: Mechanics and Dynamics of Cell Movements: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Fletcher
Terms offered: Fall 2024, Spring 2024, Fall 2023
The mechanisms that link cellular differentiation programs and dynamic gene regulation in complex eukaryotic systems remain mysterious. Such programs drive diverse and central biological processes including organismal development, immune function, disease progression, and meiosis. This course is focused on the molecular basis for the cellular remodeling accompanying meiosis, the highly conserved process by which gametes are produced.
The Regulation of Meiotic Gene Expression and Cellular Morphogenesis: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Brar
The Regulation of Meiotic Gene Expression and Cellular Morphogenesis: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Spring 2018
Review of relevant literature and discussion of ongoing research: cytoskeletal regulation and mRNA transport in glia; organelle biogenesis and homeostasis, including of Golgi outposts; myelination in learning and behavior; gliovascular development; biophysics of liquid condensates; mechanisms of neurological disease.
Research Review in Cell and Developmental Biology: Glial Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Fu
Research Review in Cell and Developmental Biology: Glial Cell Biology: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of current literature and discussion of original research.
Research Review in Cell and Developmental Biology: Cell Morphogenesis: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Heald
Research Review in Cell and Developmental Biology: Cell Morphogenesis: Read Less [-]
Terms offered: Spring 2015, Fall 2014, Spring 2014
Review of current literature and discussion of original research.
Research Review in Cell and Developmental Biology: Nucleocytoplasmic Transport: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Weis
Research Review in Cell and Developmental Biology: Nucleocytoplasmic Transport: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of current literature and discussion of original research.
Research Review in Cell and Developmental Biology: Signal Transduction and Tumor Suppressor Genes: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Luo
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of relevant literature and discussion of current research: Mitochondrial dynamics, transport and inheritance; replication, segregation and distribution of mitochondrial genomes; underlying mechanisms of human mitochondrial disease.
Research Review in Cell and Developmental Biology: Mitochondrial biology: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Lewis
Research Review in Cell and Developmental Biology: Mitochondrial biology: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Identifying pathways that restrict growth and cell proliferation in vivo.
Research Review in Cell and Developmental Biology: Mechanisms of Control of Growth and Cell Proliferation: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Hariharan
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of current literature and discussion of original research.
Research Review in Cell and Developmental Biology: Cytoskeleton and Cell Motility: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Welch
Research Review in Cell and Developmental Biology: Cytoskeleton and Cell Motility: Read Less [-]
Terms offered: Fall 2023, Spring 2023, Fall 2022
Review of current literature and discussion of original research.
Research Review in Cell and Developmental Biology: Steroid Hormone and Growth Factor Action: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Firestone
Terms offered: Fall 2024, Spring 2024, Fall 2023
Cell surface growth with emphasis on the unicellular eukaryote S. cerevisiae.
Research Review in Cell and Developmental Biology: Secretion and Cell Membrane Assembly: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Schekman
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of current literature and discussion of original research.
Research Review in Cell and Developmental Biology: Assembly and Subcellular Organization of Bacterial Organelles: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Komeili
Terms offered: Fall 2024, Spring 2024, Fall 2023
Malignant transformation represents the endpoint of successive genetic lesions that confer uncontrolled proliferation and survival, unlimited replicative potential, and invasive growth.
Research Review in Cell and Developmental Biology: MicroRNA Functions in Cancer Development, Mouse Tumor Models: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: He
Terms offered: Fall 2024, Spring 2024, Fall 2023
Inheritance, chromatin structure, gene expression, and the organization of chromosomes in the nucleus.
Research Review in Cell and Developmental Biology: Cancer Biology: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Karpen
Research Review in Cell and Developmental Biology: Cancer Biology: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of current literature and discussion of current research. Current research focuses on regulation of energy metabolism and the effect of changes in energy metabolism induced by diet and exercise on age-associated functional decline of organisms.
Research Review in Cell and Developmental Biology: Energy Metabolism and Aging: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Titov
Research Review in Cell and Developmental Biology: Energy Metabolism and Aging: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Mechanisms underlying the establishment and maintenance of cellular organization in epithelia and other cell types.
Research Review in Cell and Developmental Biology: Regulation of Cell Polarity in Drosophila: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Bilder
Terms offered: Fall 2024, Spring 2024, Fall 2023
The goal of our laboratory is to understand the key functions of telomeres and telomerase in tissue homeostasis, tumorigenesis, and aging. To this end, we generate genetically engineered human pluripotent and adult stem cell models to measure telomere and telomerase function during cellular differentiation and tumor formation.
Research Review in Cell and Developmental Biology: Telomere Biology of Human Stem Cells: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Hockemeyer
Terms offered: Fall 2024, Spring 2024, Fall 2023
Current research examines the control mechanisms of how cells behave, how cells talk to one another, and how cells sense, change, and maintain their space in the context of organogenesis.
Research Review in Cell and Developmental Biology: Organ Formation and Function in Zebrafish: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Swinburne
Terms offered: Fall 2023, Spring 2023, Fall 2022
Research in our lab is focused on the cell biology of mammalian fertilization. Our lab uses biophysical, biochemical, and molecular genetics methods to study sperm ion channels and transporters that regulate sperm motility, chemotaxis, and the acrosome reaction. A better understanding of these processes will eventually lead to the development of effective tools to control and preserve male fertility, improve the reproductive health of human population worldwide, and advance family planning.
Research Review in Cell and Developmental Biology: The Cell Biology of Fertilization: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Lishko
Research Review in Cell and Developmental Biology: The Cell Biology of Fertilization: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of current literature and discussion of current research.
Research Review in Cell and Developmental Biology: The Cytoskeleton and Morphogenesis: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2-0 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Drubin
Research Review in Cell and Developmental Biology: The Cytoskeleton and Morphogenesis: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of current literature and discussion of current research. Current research focuses on elucidating the molecular mechanisms of somatosensory mechanotransduction.
Research Review in Cell and Developmental Biology: Molecular Mechanisms of Transduction in Touch and Pain Receptors: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Bautista
Terms offered: Fall 2023, Spring 2023, Fall 2022
Review of current literature and discussion of original research.
Research Review in Cell and Developmental Biology: Leech Embryology and Development: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Weisblat
Research Review in Cell and Developmental Biology: Leech Embryology and Development: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
How chromosomes are reorganized during melosis to accomplish the pairing, recombinatin, and segregation leading up to successful gamete production.
Research Review in Cell and Developmental Biology: Chromosome Remodeling and Reorganization During Meiosis: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Dernburg
Terms offered: Spring 2024, Spring 2023, Spring 2022
Principles and practice of classical and modern genetic analysis as applied to eukaryotic organisms, including yeast, nematodes, , mice and humans; isolation and analysis of mutations; gene mapping; suppressor analysis; chromosome structure; control of gene expression; and developmental genetics.
Advanced Genetic Analysis: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing with 110 or 140 or consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructors: Koshland, Meyer
Terms offered: Fall 2024, Spring 2024, Fall 2023
This graduate seminar consists of weekly presentations from Berkeley graduate students as well as outside speakers on topics surrounding evolution, genetics, and genomics. Many labs spread across different departments have research programs focused on evolution, genetics, and genomics. However, it can be challenging to keep abreast of this research and to identify potential collaborations due to the dispersion of labs across different departments and specialties. The Center for Theoretical and Evolutionary Genetics (CTEG) is an informal group of labs that collectively work on genetics and genomics. The seminar seeks to provide a common space for graduate students to present their research and learn about the research of their colleagues.
CTEG Evolution, Genetics, and Genomics Seminar: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructors: Sudmant, Moorjani
Also listed as: INTEGBI C242
CTEG Evolution, Genetics, and Genomics Seminar: Read Less [-]
Terms offered: Spring 2015, Spring 2014
A graduate seminar class in which a group of students will closely examine recent computational methods in high-throughput sequencing followed by directly examining interesting biological applications thereof.
Seq: Methods and Applications: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing in Math, MCB, and Computational Biology; or consent of the instructor
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructor: Pachter
Also listed as: MATH C243
Terms offered: Spring 2013
Introduction to algebraic statistics and probability, optimization, phylogenetic combinatorics, graphs and networks, polyhedral and metric geometry.
Discrete Mathematics for the Life Sciences: Read More [+]
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Also listed as: MATH C239
Terms offered: Fall 2024, Spring 2024, Spring 2014
This course explores experimental and computational approaches to studying the sequence to function relationships of intrinsically disordered proteins. Emphasis on the activation domains of transcription factors. High-throughput experiments, machine learning, evolutionary comparisons, and all atom simulations will be discussed. Additional emphasis will be placed on characterizing the functional consequences of patient mutations in activation domains.
Research in Genetics and Development: From Sequence to Function in Transcription Factors: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Staller
Terms offered: Fall 2024, Spring 2024, Fall 2023
Central to the aging process is the unfolding of the proteome. Specific areas under study include cellular responses to protein misfolding and coordination of these responses across an organism.
Research Review in Genetics and Development: Aging and Protein Homeostasis: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Dillin
Research Review in Genetics and Development: Aging and Protein Homeostasis: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Biochemical and molecular genetic aspects of eukaryotic messenger RNA splicing and transposition, with an emphasis on as an experimental system.
Research Review in Genetics and Development: Nucleic Acid-Protein Interactions and Control of Gene Expression: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Rio
Terms offered: Fall 2023, Spring 2023, Fall 2022
Genes, gene products and molecular mechanisms that control cell types in the unicellular eukaryote .
Research Review in Genetics and Development: Mechanisms of Genetic Regulation in Yeast: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Rine
Terms offered: Fall 2024, Spring 2024, Fall 2023
Molecular and genetic approaches to the problem of how neurons develop, with emphasis on and .
Research Review in Genetics and Development: Neuronal Development: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Garriga
Research Review in Genetics and Development: Neuronal Development: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
We study how genes control pattern formation during development and pattern modification during evolution.
Research Review in Genetics and Development: Developmental and Evolutionary Genetics: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Miller
Research Review in Genetics and Development: Developmental and Evolutionary Genetics: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
This course focuses on understanding 1) how cellular aging is affected during gametogenesis, the developmental program that produces gametes for sexual reproduction and 2) how chromosome segregation is regulated during meiosis, the specialized cell division that generates gametes.
Investigating Cellular Aging and Chromosome Segregation during Gametogenesis: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Unal
Investigating Cellular Aging and Chromosome Segregation during Gametogenesis: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Research focuses on use of statistical and computational approaches to study questions in human genetics and evolutionary biology. This includes, but is not limited to, studying (1) how different evolutionary processes such as mutation rate evolve across primates, (2) when key events (such as introgression and adaptations) occurred in human history, and (3) how we can leverage large-scale datasets to identify genetic variants related to human adaptation and disease.
Research Review in Genetics and Development: Human Population Genetics and Evolutionary Biology: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Moorjani
Terms offered: Fall 2024, Spring 2024, Fall 2023
How does the sequence of an RNA determine its post-transcriptional regulation? Genomic and systems biology investigations of alternative splicing, translation, and other post-transcriptional regulatory processes.
Research Review in Genetics and Development: RNA Systems Biology: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Lareau
Research Review in Genetics and Development: RNA Systems Biology: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Molecular and genetical analysis of sex determination and dosage compensation in the nematode .
Research Review in Genetics and Development: Developmental and Molecular Genetics of C. elegans: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Meyer
Terms offered: Fall 2024, Spring 2024, Fall 2023
Evaluation of current research on choanoflagellates, sponges, and animal origins. Intended to complement ongoing research for graduate students.
Research Review in Genetics and Development: Animal Origins: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: King
Research Review in Genetics and Development: Animal Origins: Read Less [-]
Terms offered: Fall 2023, Spring 2023, Fall 2022
Review of current literature and discussion of current research.
Research Review in Genetics and Development: Saccharomyces Cerevisiae Microtubule Cytoskeleton: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Barnes
Terms offered: Fall 2024, Spring 2024, Fall 2023
Research review in genetics, genomics and development. In development a single cell goes through a series of repeated divisions
and these cells read the program encoded in their DNA in order to become
familiar cell types such as those found in muscle, liver, or our brains. The
goal of our lab is to uncover the rules behind these decisions with the
objective of predicting and manipulating developmental programs from just
looking at DNA sequence. In order to reach this predictive understanding we
combine physics, synthetic biology, and new technologies to query and
control developmental decisions in real time at the single cell level in
the fruit fly embryo.
Physical Biology of Living Organisms: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Garcia
Terms offered: Fall 2024, Spring 2024, Fall 2023
Biochemistry, cancer biology and virology, cell biology, computational biology, genetics, microbiology, molecular and cell physiology.
Research Review in Genetics and Development: Genome Sequences: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Eisen
Research Review in Genetics and Development: Genome Sequences: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of current literature and discussion of original research in the evolution of genome structure, aging, and cellular and organismal diversity.
Research Review in Genetics and Development: Evolution of Genome Structure and Cellular Diversity: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Sudmant
Terms offered: Fall 2024, Spring 2024, Fall 2023
Recent developments in computational methods for genomics and their application for understanding the structure and function of genes encoded in completely sequenced genomes.
Research Review in Genetics and Development: Computational Genomics: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Brenner
Research Review in Genetics and Development: Computational Genomics: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Topics on gene regulatory network control of neural crest cell differentiation during development, vertebrate evolution, and tissue regeneration will be discussed.
Research Review in Genetics and Development: Vertebrate development and tissue regeneration: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Martik
Terms offered: Fall 2024, Spring 2024, Fall 2023
Comparative analysis of eukaryotic genomes to inform the origins and diversification of animals and plants.
Research Review in Genetics, Genomics and Development: Evolution of Genomes: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Rokhsar
Research Review in Genetics, Genomics and Development: Evolution of Genomes: Read Less [-]
Terms offered: Fall 2023, Spring 2023, Fall 2022
The Roelink laboratory is interested in the mechanisms of embryonic induction, the phenomenon in which a group of cells changes the developmental fate of neighboring cells via the release of inducers.
Research Review in Genetics and Development: Induction in Vertebrate Development and ES Cell Differentiation: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Roelink
Terms offered: Fall 2024, Spring 2024, Fall 2023
Discussions pertaining to the development of new genetic tools for archaeal model organisms with a particular emphasis on methane metabolizing archaea in order to characterize their physiology, evolution and metabolism.
Research Review in Genetics and Development: Archaeal Genetics and Methane Metabolism: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Nayak
Research Review in Genetics and Development: Archaeal Genetics and Methane Metabolism: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
This course will focus on mechanisms of gene control in vertebrate animals, particularly in the area of vertebrate development. Amphibian egg formation, mesoderm induction, neural induction, and patterning of the nervous system at the molecular level. Control of transcription, post-transcriptional control of gene expression (including control of RNA turnover and RNA localization).
Research Review in Genetics and Development: Mechanisms of Gene Control in Vertebrate Animals: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Harland
Formerly known as: 218Y
Terms offered: Fall 2024, Spring 2024, Fall 2023
Use of genetic, cell biological, and biochemical approaches in budding yeast to understand genome integrity, genome evolution, and most recently desiccation tolerance.
Research Review in Genetics and Development: Chromosome Structure and Integrity, Genome Evolution: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Koshland
Terms offered: Spring 2024, Spring 2023, Spring 2022
Molecular and cellular analysis of the immune response emphasizing concepts and methodology. Innate immunity, pathogen sensors, antibodies and T cell receptors, lymphocyte activation, tolerance and selection. Antigen processing, T cell subtypes, and T regulatory cells. NK cells, tumor surveillance, and AIDS.
Advanced Immunology: Read More [+]
Rules & Requirements
Prerequisites: 100, 110, 140, 150 or consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Terms offered: Spring 2022, Spring 2021, Fall 2020
This is an advanced seminar course which will consider current research questions and experimental approaches in molecular and cellular immunology. Each registrant will present a 30-minute research talk describing the problems they are studying, the approach they are taking, their preliminary data, and technical problems. Other course participants (including basic immunology faculty) will provide criticism and suggestions.
The Regulation of Immune System Development and Function: Read More [+]
Rules & Requirements
Prerequisites: 250 or consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Winoto
The Regulation of Immune System Development and Function: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
The TB field has entered a new era with the convergence of genetic tools, genome sequencing, bioinformatics, advanced imaging techniques, animal models of infection, and high-throughput assays that allow us to study this multi-faceted interaction between Mtb and its host. We use all of these tools to probe the molecular and cellular events that enable M. tuberculosis to evade host defense mechanisms.
Mycobacterium Tuberculosis (Mtb): Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Cox
Terms offered: Fall 2024, Spring 2024, Fall 2023
In this course we will discuss our research as well as recent literatures focusing on understanding of 1) How is homeostasis in the CNS regulated by innate immune functions of microglia? 2) How can we intervene in dysfunction of microglia-mediated immune functions using NRs signaling and transcription?
Research Review in Immunology and Pathogenesis: Nuclear Receptor-Mediated Regulation of Neuroinflammation: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Saijo
Terms offered: Fall 2024, Spring 2024, Fall 2023
We will discuss macrophage biology and innate immunity in the context of infection with *Mycobacterium tuberculosis* through
discussion of current research from the Stanley Lab and both cutting edge and classic literature in relevant fields.
Research Review in Immunology and Pathogenesis: Mycobacterial Biology and Host-Pathogen Interactions: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Stanley
Terms offered: Spring 2024, Fall 2023, Spring 2023
Molecular biology of T cell receptor genes and their transcription controlling proteins/genes. Programmed cell death during thymocyte differentiation.
Research Review in Immunology and Pathogenesis: Regulation of T Cell Receptor Genes Expression: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Winoto
Terms offered: Fall 2024, Spring 2024, Fall 2023
Molecular and biological basis for recognition by natural killer cells and T cells.
Research Review in Immunology and Pathogenesis: Natural Killer (NK) Cell and T Cell Receptors: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Raulet
Terms offered: Fall 2024, Spring 2024, Fall 2023
Molecular and cellular aspects of thymocyte differentiation.
Research Review in Immunology and Pathogenesis: T Cell Development: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Robey
Research Review in Immunology and Pathogenesis: T Cell Development: Read Less [-]
Terms offered: Fall 2023, Fall 2022, Fall 2021
Molecular basis of terminal B cell differentiation. Role of transcription factors in B cell activation.
Research Review in Immunology and Pathogenesis: B Cell Differentiation: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Sha
Research Review in Immunology and Pathogenesis: B Cell Differentiation: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
The mechanisms used by viruses to counteract the pressure of the immune system.
Research Review in Immunology and Pathogenesis: Immune Evasion by Viruses: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Coscoy
Research Review in Immunology and Pathogenesis: Immune Evasion by Viruses: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Intersecting the fields of cancer biology, immunology, and epigenetics to strengthen our own immune defense mechanisms against our own cancers by reprogramming T cell function specifically within the tumor microenvironment.
Research Review in Immunology and Pathogenesis: Epigenetic Control for Regulatory T Cell Function in Cancer and Autoimmunity: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Dupage
Terms offered: Fall 2024, Spring 2024, Fall 2023
Innate immunity and innate control of adaptive immunity.
Research Review in Immunology and Pathogenesis: Innate Immunity and Innate Control of Adaptive Immunity: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Barton
Terms offered: Fall 2024, Spring 2024, Fall 2023
Role of innate host responses in defense against intracellular bacterial pathogens.
Research Review in Immunology and Pathogenesis: Immunology, Microbiology, and Genetics of Bacterial Pathogenesis: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Vance
Terms offered: Fall 2024, Spring 2024, Fall 2023
We will discuss circadian rhythms research, at the behavioral, tissue and molecular scales. Our main focus is the circadian regulation of gene expression and its impact in host physiology. We will also focus on malaria and sleeping sickness infections, understanding the clinical aspects, the immune response to parasites and the vector transmission.
Research Review in Immunology and Pathogenesis: Circadian rhythms in Parasitic Diseases: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Rijo-Ferreira
Terms offered: Fall 2024, Spring 2024, Fall 2023
Cellular biology and genetics of retroviral infection and cellular antiviral mechanisms. Functional genomics approaches in key host/virus interactions.
Research Review in Immunology and Pathogenesis: Cellular barriers to retroviral infection: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: OhAinle
Terms offered: Fall 2023, Fall 2022, Fall 2021
This course covers the molecular/cellular basis of neuron excitability (membrane potentials, action potential generation and propagation, ion channels), synaptic transmission and plasticity, sensory receptor function, and developmental neurobiology.
Cellular and Developmental Neurobiology: Read More [+]
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Also listed as: NEUROSC C261
Terms offered: Fall 2024, Spring 2024, Fall 2023
Research in our laboratory focuses on understanding how neurons use biochemical pathways to integrate diverse types of information in order to adjust synaptic strength and modulate neuronal excitability, and how these interactions go awry in disease. To investigate this we are taking a multi-disciplinary approach incorporating molecular, biochemical, imaging, and electrophysiological analyses in mouse and human cells.
Research Review in Neurobiology: Molecular Mechanisms of Neuronal Plasticity: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Bateup
Research Review in Neurobiology: Molecular Mechanisms of Neuronal Plasticity: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of recent research in molecular mechanisms involved in intracellular and extracellular signaling in the nervous system.
Research Review in Neurobiology: Signaling Within and Between Neurons: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Kramer
Research Review in Neurobiology: Signaling Within and Between Neurons: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of research in molecular and biophysical aspects of sensory transduction and electrical signaling in the nervous system.
Molecular and Biophysical Neuroscience: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of the instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Brohawn
Terms offered: Fall 2024, Spring 2024, Fall 2023
Research review in neurobiology. Review of recent optogenetic strategies for dissecting neural connectivity, function, and dysfunction in the rodent and primate brain.
Optogenetic Dissection of Neural Circuits: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Lammel
Terms offered: Fall 2024, Spring 2024, Fall 2023
Development and application of optical imaging methods for clearer, deeper, and faster imaging of biological tissue in vivo, including a critical review of the current research.
Research Review in Development and Application of Advanced Methods for In Vivo Imaging: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Ji
Terms offered: Fall 2024, Spring 2024, Fall 2023
The basic investigation of neural differentiation of stem cells, as well as the
use of stem cells and gene delivery for neuroregeneration.
Research Review in Neurobiology: Stem Cells and Gene Therapy in the Nervous System: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Schaffer
Research Review in Neurobiology: Stem Cells and Gene Therapy in the Nervous System: Read Less [-]
Terms offered: Fall 2023, Spring 2023, Fall 2022
The molecular and cellular basis of taste perception in the model organism .
Research Review in Neurobiology: Taste Recognition in Drosophila: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Scott
Research Review in Neurobiology: Taste Recognition in Drosophila: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Molecular and circuit studies of the mechanisms that specify synaptic properties and how these properties bias the timescales of neuronal computation.
Research Review in Neurobiology: Instructive Cues for Neural Form and Function: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Gomez
Research Review in Neurobiology: Instructive Cues for Neural Form and Function: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Drosophila mutants that have behavioral abnormalities to unravel new and basic features of nervous system structure and function.
Research Review in Neurobiology: Insect Neurophysiology: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Tanouye
Research Review in Neurobiology: Insect Neurophysiology: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Research in the Fisher laboratory focuses on spatial navigation in fruit flies in order to understand how nervous systems flexibly process information. Our research combines in vivo electrophysiology, 2-photon imaging, advanced genetic approaches and quantitative behavioral analysis to understand how the fly’s brain constructs and maintains a sense of direction under ever-changing conditions.
Research Review in Neurobiology: Synaptic and Circuit Mechanisms that Support Spatial Navigation: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Fisher
Terms offered: Fall 2024, Spring 2024, Fall 2023
Microcircuitry of the cerebral cortex that underlies sensory processing and adaptive behavior.
Research Review in Neurobiology: Neural Circuits for Sensory Processing and Behavior: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Adesnik
Research Review in Neurobiology: Neural Circuits for Sensory Processing and Behavior: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Mechanisms for visual object representation including recognition, memory, segmentation, tracking, 3D representation, and embedding into meaningful scenes. Understanding the function of feedforward and feedback pathways in vision.
Research Review in Neurobiology: Visual Neuroscience: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Tsao
Research Review in Neurobiology: Visual Neuroscience: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
How the cerebral cortex processes sensory input and stores information about the sensory world. We focus on the rat's primary somatosensory (S1) cortex.
Research Review in Neurobiology: Sensory Processing and Plasticity in Cerebral Cortex: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Feldman
Research Review in Neurobiology: Sensory Processing and Plasticity in Cerebral Cortex: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of current literature and discussion of original research.
Research Review in Neurobiology: Potassium Channels and Synaptic Plasticity: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Isacoff
Research Review in Neurobiology: Potassium Channels and Synaptic Plasticity: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Review of current literature and discussion of original research.
Research Review in Neurobiology: Processing of Visual Information in the Mammalian Brain: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Dan
Terms offered: Fall 2024, Spring 2024, Fall 2023
How neural activity affects the assembly of neural circuits.
Research Review in Neurobiology: Neural Activity Affecting the Assembly of Neural Circuits: Read More [+]
Rules & Requirements
Prerequisites: Enrollment is restricted to students conducting research in the laboratory of the instructor, or requires consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Feller
Terms offered: Not yet offered
This course offers an introduction to the field of biotechnology and will cover the history of the field, its impact on medicine and society, key methodologies, important therapeutic areas, and the range of career options available in the biopharmaceutical industry. Students will hear from lecturers with expertise ranging from molecular biology to clinical trial design and interpretation and be given an integrated overview of a complex area. Students will actively participate in experiential learning about relevant topics and presenting their findings in class, which will deepen understanding. There will be interactive elements, using a Socratic discussion format. Students are expected to participate actively.
Therapeutics Development in Biotech: Financing, Regulation and Social Ethics: Read More [+]
Rules & Requirements
Prerequisites: Students must be enrolled in the Master of Biotechnology program
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructor: Schaletzky
Therapeutics Development in Biotech: Financing, Regulation and Social Ethics: Read Less [-]
Terms offered: Fall 2021, Spring 2020, Spring 2019
This course will cover several aspects of communicating quantitative information, with a primary focus on visualizations for publications, presentations, and posters. Other topics include sharing of data and analyses, such as new publication models and interactive notebooks, as well as lifecycle data management and publication. Primary discussion will be on conceptual issues, and students will be expected to use various systems and resources as self-directed homestudy.
Communicating Quantitative Information: Read More [+]
Hours & Format
Fall and/or spring: 15 weeks - 1.5 hours of seminar and 1.5 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructor: Brenner
Also listed as: PLANTBI C277
Terms offered: Spring 2022, Spring 2012, Spring 2011
The course will focus on fundamental principles, essential concepts, and recent advances in select topics in molecular and cell biology. Topics include genomics and computational biology, molecular evolution, neurons and synapses, microbi ology and immunology, macromolecular structure and function, and scientific writing. Courses are taught in tandem and maybe taken individually.
Selected Topics in Molecular and Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing or consent of instructor
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 5 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Selected Topics in Molecular and Cell Biology: Read Less [-]
Terms offered: Spring 2012, Spring 2011, Spring 2010
The course will focus on fundamental principles, essential concepts, and recent advances in select topics in molecular and cell biology. Topics include genomics and computational biology, molecular evolution, neurons and synapses, microbi ology and immunology, macromolecular structure and function, and scientific writing. Courses are taught in tandem and maybe taken individually.
Selected Topics in Molecular and Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing and consent of instructor
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 5 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Selected Topics in Molecular and Cell Biology: Read Less [-]
Terms offered: Spring 2022, Spring 2021, Spring 2016
The course will focus on fundamental principles, essential concepts, and recent advances in select topics in molecular and cell biology. Topics include genomics and computational biology, molecular evolution, neurons and synapses, microbi ology and immunology, macromolecular structure and function, and scientific writing. Courses are taught in tandem and maybe taken individually.
Selected Topics in Molecular and Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing and consent of instructor
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 5 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Selected Topics in Molecular and Cell Biology: Read Less [-]
Terms offered: Fall 2024, Fall 2023, Fall 2022
The course will focus on fundamental principles, essential concepts, and recent advances in select topics in molecular and cell biology. Topics include genomics and computational biology, molecular evolution, neurons and synapses, microbi ology and immunology, macromolecular structure and function, and scientific writing. Courses are taught in tandem and maybe taken individually.
Selected Topics in Molecular and Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing or consent of instructor
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 5 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Selected Topics in Molecular and Cell Biology: Read Less [-]
Terms offered: Spring 2012, Spring 2011, Spring 2010
The course will focus on fundamental principles, essential concepts, and recent advances in select topics in molecular and cell biology. Topics include genomics and computational biology, molecular evolution, neurons and synapses, microbi ology and immunology, macromolecular structure and function, and scientific writing. Courses are taught in tandem and maybe taken individually.
Selected Topics in Molecular and Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing and consent of instructor
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 5 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Selected Topics in Molecular and Cell Biology: Read Less [-]
Terms offered: Fall 2016, Spring 2012, Spring 2011
The course will focus on fundamental principles, essential concepts, and recent advances in select topics in molecular and cell biology. Topics include genomics and computational biology, molecular evolution, neurons and synapses, microbi ology and immunology, macromolecular structure and function, and scientific writing. Courses are taught in tandem and maybe taken individually.
Selected Topics in Molecular and Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing and consent of instructor
Repeat rules: Course may be repeated for credit when topic changes.
Hours & Format
Fall and/or spring: 5 weeks - 3 hours of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Selected Topics in Molecular and Cell Biology: Read Less [-]
Terms offered: Spring 2022, Spring 2021, Spring 2020
Data science is rapidly becoming a critical skill for molecular and cell biologists. This course provides a survey of data science concepts and methods, including practical statistical inference and modeling, data visualization and exploration, elementary machine learning, and simulation. The course is practically oriented. Diverse real-world datasets, along with simulated data, will be used to develop skills and intuition.
Data Science for Molecular and Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing in the biological sciences or permission from instructors. Prior introductory exposure to programming is desired, e.g., through Data Science 8, MCB Python “boot camp,” or self taught from introductory programming tutorials. Please see http://python.berkeley.edu/resources/ for suggested resources. No prior statistics is assumed. The course is not suitable for students with advanced training in statistics or machine learning
Repeat rules: Course may be repeated for credit with instructor consent.
Hours & Format
Fall and/or spring: 15 weeks - 4 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructors: Rokhsar, Eisen
Terms offered: Not yet offered
This capstone course fosters collaborative learning by bringing together students each week to discuss their internship project that they have been working on individually or in small groups under the supervision of their internship mentor. Students are encouraged to apply critical thinking skills to evaluate other projects and to provide constructive feedback. Students will work towards a final written report and oral presentation. They will identify and present a technology overview, explanation of unmet need, a central working hypothesis, a plan to test said hypothesis, execution of their plan, and a final research product. The final presentation will be in a poster presentation format.
Master of Biotechnology Capstone Course: Read More [+]
Rules & Requirements
Prerequisites: MCELLBI 201A and MCELLBI 201B. Students must be enrolled in the Master of Biotechnology program
Hours & Format
Fall and/or spring: 15 weeks - 5 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructor: Luo
Terms offered: Spring 2024, Fall 2023, Spring 2023
Graduate student presentations on selected research topics in molecular and cell biology. Several sections covering different topics offered each semester. Concurrent enrollment in more than one section is permitted. List of topics to be announced before each semester.
Graduate Seminar: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing in the department or consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 1-2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Terms offered: Fall 2024, Fall 2023, Fall 2022
Closely supervised experimental work under the direction of an individual faculty member; an introduction to experimental methods and research approaches in particular areas of molecular and cell biology.
Introduction to Research: Read More [+]
Rules & Requirements
Prerequisites: Consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 2-12 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade. This is part one of a year long series course. A provisional grade of IP (in progress) will be applied and later replaced with the final grade after completing part two of the series.
Terms offered: Spring 2024, Spring 2023, Spring 2022
Closely supervised experimental work under the direction of an individual faculty member; an introduction to experimental methods and research approaches in particular areas of molecular and cell biology.
Introduction to Research: Read More [+]
Rules & Requirements
Prerequisites: Consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 2-12 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade. This is part two of a year long series course. Upon completion, the final grade will be applied to both parts of the series.
Terms offered: Fall 2024, Spring 2024, Fall 2023
Individual research under the supervision of a faculty member.
Research: Read More [+]
Rules & Requirements
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 0 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Terms offered: Summer 2009 10 Week Session, Summer 2008 10 Week Session, Summer 2006 10 Week Session
Individual research under the supervision of a staff member.
Research: Read More [+]
Rules & Requirements
Prerequisites: Consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Summer: 8 weeks - 3-6 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Terms offered: Fall 2024, Fall 2023, Fall 2022
Seminar on presentation and evaluation of results in area of student's individual research interests.
Research Seminar: Read More [+]
Rules & Requirements
Prerequisites: Concurrent enrollment in 291A or 292
Hours & Format
Fall and/or spring: 15 weeks - 3 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Terms offered: Spring 2024, Fall 2023, Spring 2023
The purpose of this course is to ensure that research trainees receive ample training in Responsible Conduct in Research. Students also gain an understanding of federal, state, and UC Berkeley policies and resources available to further support their research endeavors.
Responsible Conduct in Research: Read More [+]
Rules & Requirements
Prerequisites: Consent of instructor
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 1.5 hours of lecture and 1.5 hours of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Sharma
Terms offered: Prior to 2007
The purpose of this course is to ensure that research trainees receive training in Rigor and Reproducibility in Research. Students also gain an understanding of federal, state, and UC Berkeley policies and resources available to further support their research endeavors.
Rigor and Reproducibility in Research: Read More [+]
Rules & Requirements
Prerequisites: Consent of Instructor
Hours & Format
Fall and/or spring: 15 weeks - 1.5 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Sharma
Terms offered: Prior to 2007
This refresher course will cover topics in responsible conduct in research drawing from case studies of the Association of American Medical Colleges and the NIH. Students will review case studies in preparation for class discussion. Required of all 4th year MCB graduate students funded on NIH training grants.
Responsible Conduct of Research Refresher: Read More [+]
Objectives & Outcomes
Course Objectives: Collaborative research including collaborations with industry
Data acquisition and laboratory tools; management, sharing and ownership
Mentor/mentee responsibilities and relationships
Policies regarding human subjects, live vertebrate animal subjects in research, and safe laboratory
practices
Research misconduct and policies for handling misconduct
Responsible authorship and publication
The scientist as a responsible member of society, contemporary ethical issues in biomedical research, and
the environmental and societal impacts of scientific research
Rules & Requirements
Prerequisites: Consent of instructor. Must be a 4th year MCB graduate student
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructor: Sharma
Terms offered: Fall 2018, Spring 2018
This course is designed to introduce students to the foundations of statistics in the context of biological research. Rather than focusing on a catalog of specific methods (by essence non-exhaustive and rapidly outdated), the course emphasizes general concepts and approaches necessary for sound statistical practice. Topics covered include: exploratory data analysis (EDA); data visualization; inferential reasoning; models and assumptions; statistical computing; computationally reproducible research. The statistical methods and software are motivated by and illustrated on data structures that arise in current biological and medical research.
Foundations of Biostatistical Practice: Read More [+]
Rules & Requirements
Prerequisites: Consent of instructor
Hours & Format
Fall and/or spring: 15 weeks - 1 hour of lecture and 1 hour of discussion per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Terms offered: Fall 2022, Fall 2021, Spring 2021
This course will discuss cutting-edge topics in biochemistry, structural biology, cell biology, developmental biology and genetics. Lectures will be given by internationally recognized biomedical scientists that visit the Molecular and Cell Biology Department and present work currently performed in their laboratories. The class will include topics ranging from structural analysis of important signaling molecules, live cell imaging and high resolution microscopy of critical cellular structures, to genetic dissection of essential signaling networks in cells and developmental pathways in multicellular organisms. It is the goal of this class to expose students to both the breadth and highest standards of current biomedical research.
Current Topics in Biomedical Sciences: Read More [+]
Rules & Requirements
Prerequisites: Molecular and Cell Biology graduate students only
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of lecture per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Terms offered: Spring 2024, Spring 2023, Spring 2022
This course is designed to assist graduate students in the biological sciences with planning their postgraduate careers. Weekly guest speakers will present their experiences on a variety of topics. Postdoctoral students are invited. Topics may include academia; job searches; setting up a laboratory; patent law/technology transfer; public policy/regulatory affairs; bioinformatics; science writing/technical support; forensic science; postdoctoral positions in industry; teaching, and other topics of interest.
Careers for Life Sciences Ph.D's: Read More [+]
Rules & Requirements
Prerequisites: Open to graduate and postdoctoral students
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Terms offered: Spring 2020, Spring 2019, Spring 2018
Meetings for the presentation of original work by faculty, visiting lecturers, and graduate students.
Molecular and Cell Biology Colloquium: Read More [+]
Hours & Format
Fall and/or spring: 15 weeks - 1.5 hours of colloquium per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Offered for satisfactory/unsatisfactory grade only.
Terms offered: Spring 2024, Fall 2022, Fall 2021
This interactive seminar builds skills, knowledge and community in computational biology for first year PhD and second year Designated Emphasis students. Topics covered include concepts in human genetics/genomics, microbiome data analysis, laboratory methodologies and data sources for computational biology, workshops/instruction on use of various bioinformatics tools, critical review of current research studies and computational methods, preparation for success in the PhD program and career development. Faculty members of the graduate program in computational biology and scientists from other institutions will participate. Topics will vary each semester.
Doctoral Seminar in Computational Biology: Read More [+]
Rules & Requirements
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 2 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate
Grading: Letter grade.
Instructors: Moorjani, Rokhsar
Also listed as: CMPBIO C293
Terms offered: Prior to 2007
This course introduces new graduate student instructors to effective teaching methods that they can use in their MCB courses. Through readings, discussions and demonstrations, students will learn how to engage and motivate students, facilitate active participation, plan a class period, and write exam or practice problems. Emphasis will be placed on science education literature and proven practical techniques. We will also provide support and solutions for dealing with difficult situations that may come up during the semester.
Pedagogy for MCB Graduate Student Instructors: Read More [+]
Rules & Requirements
Prerequisites: Appointment as graduate student instructor or consent of instructor
Hours & Format
Fall and/or spring: 10 weeks - 1 hour of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Professional course for teachers or prospective teachers
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructors: Ball, Beatty, Barnes
Pedagogy for MCB Graduate Student Instructors: Read Less [-]
Terms offered: Fall 2022, Spring 2016, Fall 2015
Teaching laboratories and/or discussions for Molecular and Cell Biology courses: analysis of specific format and problems. Two units of credit for those with 50% teaching appointment; one unit of credit for those with 25% teaching appointment.
Teaching of Molecular and Cell Biology: Read More [+]
Rules & Requirements
Prerequisites: Appointment as graduate student instructor or consent of instructor
Repeat rules: Course may be repeated for credit up to a total of 4 units.
Hours & Format
Fall and/or spring: 15 weeks - 0-1 hours of seminar per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Professional course for teachers or prospective teachers
Grading: Offered for satisfactory/unsatisfactory grade only.
Terms offered: Fall 2024, Spring 2024, Fall 2023
Individualized laboratory instruction.
Instrumentation in Molecular and Cell Biology: Transmission Electron Microscopy: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing; consent of instructor and sponsorship of a faculty member
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of independent study per week
Summer:
6 weeks - 2.5-10 hours of independent study per week
8 weeks - 2-7.5 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Other professional
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructors: Dernburg, Karpen
Instrumentation in Molecular and Cell Biology: Transmission Electron Microscopy: Read Less [-]
Terms offered: Fall 2024, Spring 2024, Fall 2023
Individualized laboratory instruction.
Instrumentation in Molecular and Cell Biology: Scanning Electron Microscopy: Read More [+]
Rules & Requirements
Prerequisites: Graduate standing; consent of instructor and sponsorship of a faculty member
Hours & Format
Fall and/or spring: 15 weeks - 1-4 hours of independent study per week
Summer:
6 weeks - 2.5-10 hours of independent study per week
8 weeks - 2-7.5 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Other professional
Grading: Offered for satisfactory/unsatisfactory grade only.
Instructors: Dernburg, Karpen
Instrumentation in Molecular and Cell Biology: Scanning Electron Microscopy: Read Less [-]
Terms offered: Fall 2006, Spring 2005, Spring 2001
Individual study for the comprehensive or language examinations in consultation with the field adviser.
Individual Study for Master's Students: Read More [+]
Rules & Requirements
Credit Restrictions: Course does not satisfy unit or residence requirements for master's degree.
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 1-8 hours of independent study per week
Summer: 8 weeks - 1.5-15 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate examination preparation
Grading: Offered for satisfactory/unsatisfactory grade only.
Terms offered: Spring 2006, Spring 2005, Fall 2004
Individual study in consultation with the major field adviser. Intended to provide an opportunity for qualified students to prepare themselves for the various examinations required of candidates for the Ph.D.
Individual Study for Doctoral Students: Read More [+]
Rules & Requirements
Prerequisites: Restricted to Ph.D. candidates
Credit Restrictions: Course does not satisfy unit or residence requirements for doctoral degree.
Repeat rules: Course may be repeated for credit without restriction.
Hours & Format
Fall and/or spring: 15 weeks - 0 hours of independent study per week
Summer:
6 weeks - 1-8 hours of independent study per week
8 weeks - 1-8 hours of independent study per week
Additional Details
Subject/Course Level: Molecular and Cell Biology/Graduate examination preparation
Grading: Offered for satisfactory/unsatisfactory grade only.